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MULTISPECIES: bifunctional 23S rRNA


LOCUS       WP_001086485             702 aa            linear   BCT 25-APR-2022
            (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
            (guanine(2445)-N(2))-methyltransferase RlmL [Salmonella].
ACCESSION   WP_001086485
VERSION     WP_001086485.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 702)
  AUTHORS   Jiang,M., Sullivan,S.M., Walker,A.K., Strahler,J.R., Andrews,P.C.
            and Maddock,J.R.
  TITLE     Identification of novel Escherichia coli ribosome-associated
            proteins using isobaric tags and multidimensional protein
            identification techniques
  JOURNAL   J Bacteriol 189 (9), 3434-3444 (2007)
   PUBMED   17337586
REFERENCE   2  (residues 1 to 702)
  AUTHORS   Sergiev,P.V., Bogdanov,A.A. and Dontsova,O.A.
  TITLE     Ribosomal RNA guanine-(N2)-methyltransferases and their targets
  JOURNAL   Nucleic Acids Res 35 (7), 2295-2301 (2007)
   PUBMED   17389639
REFERENCE   3  (residues 1 to 702)
  AUTHORS   Lesnyak,D.V., Sergiev,P.V., Bogdanov,A.A. and Dontsova,O.A.
  TITLE     Identification of Escherichia coli m2G methyltransferases: I. the
            ycbY gene encodes a methyltransferase specific for G2445 of the 23
            S rRNA
  JOURNAL   J Mol Biol 364 (1), 20-25 (2006)
   PUBMED   17010378
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008748.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11783
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..702
                     /gene="rlmKL"
     Protein         1..702
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0008990 - rRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /calculated_mol_wt=78718
     Region          1..702
                     /region_name="rlmL"
                     /note="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL; PRK11783"
                     /db_xref="CDD:236981"
ORIGIN      
        1 mnslfastar gleellktel eklgavgcqv vqggvhfqgd trliyqslmw srlasriilp
       61 mgeckvysdl dlylgvqain wteifnpgat favhfsglnd tirnsqygam kvkdaivdaf
      121 trknlprpnv drespdlrin vwlnketasi aldlsgdglh lrgyrdrtgl apiketlaaa
      181 ivmrsgwqpg tplldpmcgs gtllieaamw atdrapglhr ghwgfsgwaq hdetiwqevk
      241 aeaqtrarkg laeysshfyg sdsdarvier arsnarragi gelitfevkd vaqlsnplpk
      301 gpygtvisnp pygerldsep alialhsllg rtmknqfggw nlslfsaspd llgslqlrad
      361 kqfkakngpl dcvqknyhia ettadskpat vaedyanrlr knlkklekwa rqegiecyrl
      421 ydadlpeynv avdrygdwav iqeyappktv daqkarqrlf diiaatlsvl gippnklvlk
      481 trerqkgknq yqkmsekgef levseynarl wvnltdyldt glfldhriar rmlgemskgk
      541 dflnlfsytg sasvhaglgg arstttvdms rtylewaern lrlnglsgra hrliqadclg
      601 wlreaneqfd lifidpptfs nskrmeesfd vqrdhvalmk dlkrllrkgg timfsnnkrg
      661 frmdleglae lgltaqeitq ktlspdfarn rqihncwlir aa