lipopolysaccharide N-acetylmannosaminouronosyltransferase

LOCUS       WP_001064053             246 aa            linear   BCT 21-FEB-2023
            [Escherichia coli].
ACCESSION   WP_001064053
VERSION     WP_001064053.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 246)
  AUTHORS   Maczuga,N., Tran,E.N.H. and Morona,R.
  TITLE     Subcellular localization of the enterobacterial common antigen
            GT-E-like glycosyltransferase, WecG
  JOURNAL   Mol Microbiol 118 (4), 403-416 (2022)
   PUBMED   36006410
REFERENCE   2  (residues 1 to 246)
  AUTHORS   Barr,K., Ward,S., Meier-Dieter,U., Mayer,H. and Rick,P.D.
  TITLE     Characterization of an Escherichia coli rff mutant defective in
            transfer of N-acetylmannosaminuronic acid (ManNAcA) from
            UDP-ManNAcA to a lipid-linked intermediate involved in
            enterobacterial common antigen synthesis
  JOURNAL   J Bacteriol 170 (1), 228-233 (1988)
   PUBMED   3275612
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002980.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK03692
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..246
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..246
                     /gene="wecG"
     Protein         1..246
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /EC_number="2.4.1.180"
                     /GO_function="GO:0047241 - lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase activity [Evidence
                     IEA]"
                     /calculated_mol_wt=27849
     Region          4..246
                     /region_name="PRK03692"
                     /note="putative UDP-N-acetyl-D-mannosaminuronic acid
                     transferase; Provisional"
                     /db_xref="CDD:179631"
ORIGIN      
        1 mnnnttapty tlrglqligw rdmqhaldyl fadgqlkqgt lvainaekml tieenaevre
       61 linaaefkya dgisvvrsvr kkypqaqvsr vagadlweel maragkegtt vflvggkpev
      121 laqteaklrn qwnvnivgsq dgyfkpeqrq alferihasg aqivtvamgs pkqeifmrdc
      181 rlvhpdalym gvggtydvft ghvkrapkiw qtlglewlyr llsqpsrikr qlrllrylrw
      241 hytgnl