UDP-N-acetylglucosamine--undecaprenyl-phosphate

LOCUS       WP_001050972             367 aa            linear   BCT 23-MAY-2024
            N-acetylglucosaminephosphotransferase [Escherichia coli].
ACCESSION   WP_001050972
VERSION     WP_001050972.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 367)
  AUTHORS   Amer,A.O. and Valvano,M.A.
  TITLE     Conserved amino acid residues found in a predicted cytosolic domain
            of the lipopolysaccharide biosynthetic protein WecA are implicated
            in the recognition of UDP-N-acetylglucosamine
  JOURNAL   Microbiology (Reading) 147 (Pt 11), 3015-3025 (2001)
   PUBMED   11700352
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02380.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..367
                     /gene="wecA"
     Protein         1..367
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /EC_number="2.7.8.33"
                     /GO_component="GO:0009276 - Gram-negative-bacterium-type
                     cell wall [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity,
                     for other substituted phosphate groups [Evidence IEA]"
                     /GO_function="GO:0030145 - manganese ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0036380 -
                     UDP-N-acetylglucosamine-undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0009246 - enterobacterial common antigen
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=40778
     Region          7..349
                     /region_name="ECA_wecA"
                     /note="undecaprenyl-phosphate alpha-N-acetylglucosaminyl
                     1-phosphatetransferase; TIGR02380"
                     /db_xref="CDD:131433"
ORIGIN      
        1 mnlltvstdl isiflfttlf lffarkvakk vglvdkpnfr krhqgliplv ggisvyagic
       61 ftfgivdyyi phaslylaca gvlvfigald drfdisvkir atiqaavgiv mmvfgnlyls
      121 slgyifgswe mvlgpfgyfl tlfavwaain afnmvdgidg llgglscvsf aaigmilwfd
      181 gqtslaiwcf amiaailpyi mlnlgilgrr ykvfmgdags tligftviwi llettqgkth
      241 pispvtalwi iaiplmdmva imyrrlrkgm spfspdrqhi hhlimragft srqafvlitl
      301 aaallasigv laeyshfvpe wvmlvlflla fllygycikr awkvarfikr vkrrlrrnrg
      361 gspnltk