octaprenyl diphosphate synthase [Escherichia coli].

LOCUS       WP_001047341             323 aa            linear   BCT 28-MAR-2022
ACCESSION   WP_001047341
VERSION     WP_001047341.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008140.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10888
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..323
                     /gene="ispB"
     Protein         1..323
                     /product="octaprenyl diphosphate synthase"
                     /EC_number="2.5.1.90"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=35085
     Region          1..323
                     /region_name="PRK10888"
                     /note="octaprenyl diphosphate synthase; Provisional"
                     /db_xref="CDD:182813"
     Site            order(76,79..81,83..85,87..88,93..94,146,149,170..171,174,
                     211..212,215,225,230,235)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:173833"
     Site            79..88
                     /site_type="active"
                     /note="chain length determination region [active]"
                     /db_xref="CDD:173833"
     Site            order(84..85,88,93..94,149,170,211..212,215,225,230,235)
                     /site_type="active"
                     /note="substrate-Mg2+ binding site [active]"
                     /db_xref="CDD:173833"
     Site            order(84..85,88,93..94,170,211..212)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:173833"
     Site            order(84..85,88,93..94,149,170)
                     /site_type="other"
                     /note="aspartate-rich region 1"
                     /db_xref="CDD:173833"
     Site            order(90..104,218..219,225..230,233..237)
                     /site_type="active"
                     /note="active site lid residues [active]"
                     /db_xref="CDD:173833"
     Site            order(211..212,215,225,230,235)
                     /site_type="other"
                     /note="aspartate-rich region 2"
                     /db_xref="CDD:173833"
ORIGIN      
        1 mnlekinelt aqdmagvnaa ileqlnsdvq linqlgyyiv sgggkrirpm iavlaaravg
       61 yegnahvtia aliefihtat llhddvvdes dmrrgkatan aafgnaasvl vgdfiytraf
      121 qmmtslgslk vlevmseavn viaegevlql mnvndpdite enymrviysk tarlfeaaaq
      181 csgilagctp eeekglqdyg rylgtafqli ddlldynadg eqlgknvgdd lnegkptlpl
      241 lhamhhgtpe qaqmirtaie qgngrhllkp vleamnacgs lewtrqraee eadkaiaalq
      301 vlpdtpwrea liglahiavq rdr