MULTISPECIES: serine protease autotransporter toxin Pic

LOCUS       WP_001045650            1372 aa            linear   BCT 10-JUL-2019
            [Enterobacteriaceae].
ACCESSION   WP_001045650
VERSION     WP_001045650.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 1372)
  AUTHORS   Henderson,I.R., Czeczulin,J., Eslava,C., Noriega,F. and Nataro,J.P.
  TITLE     Characterization of pic, a secreted protease of Shigella flexneri
            and enteroaggregative Escherichia coli
  JOURNAL   Infect. Immun. 67 (11), 5587-5596 (1999)
   PUBMED   10531204
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR005989
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..1372
                     /gene="pic"
     Protein         1..1372
                     /product="serine protease autotransporter toxin Pic"
                     /calculated_mol_wt=146322
     Region          1..>33
                     /region_name="ESPR"
                     /note="Extended Signal Peptide of Type V secretion system;
                     pfam13018"
                     /db_xref="CDD:463773"
     Region          56..774
                     /region_name="Peptidase_S6"
                     /note="Immunoglobulin A1 protease; pfam02395"
                     /db_xref="CDD:396804"
     Region          825..1067
                     /region_name="PL1_Passenger_AT"
                     /note="Pertactin-like passenger domains (virulence
                     factors), C-terminal, subgroup 1, of autotransporter
                     proteins of the type V secretion system of Gram-negative
                     bacteria. This subgroup includes the passenger domains of
                     Neisseria and Haemophilus IgA1 proteases; cd01343"
                     /db_xref="CDD:238653"
     Region          964..1372
                     /region_name="autotrans_barl"
                     /note="outer membrane autotransporter barrel domain;
                     TIGR01414"
                     /db_xref="CDD:273608"
ORIGIN      
        1 mnkvyslkyc pvtggliavs elarrvikkt crrlthilla gipaiclcys qisqagivrs
       61 diayqiyrdf aenkglfvpg andipvydkd gklvgrlgka pmadfssvss ngvatlvspq
      121 yivsvkhngg yrsvsfgngk ntyslvdrnn hpsidfhapr lnklvtevip savtsegtka
      181 naykyteryt afyrvgsgtq ytkdkdgnlv kvaggyafkt ggttgvplis dativsnpgq
      241 tynpvngplp dygapgdsgs plfaydkqqk kwvivavlra yagingatnw wnviptdyln
      301 qvmqddfdap vdfvsglgpl nwtydktsgt gtlsqgsknw tmhgqkdndl nagknlvfsg
      361 qngaiilkds vtqgagylef kdsytvsaes gktwtgagii tdkgtnvtwk vngvagdnlh
      421 klgegtltin gtgvnpgglk tgdgivvlnq qadtagniqa fssvnlasgr ptvvlgdarq
      481 vnpdniswgy rggkldlngn avtftrlqaa dygavitnna qqksqllldl kaqdtnvsep
      541 tignispfgg tgtpgnlysm ilnsqtrfyi lksasygntl wgnslndpaq wefvgmnknk
      601 avqtvkdril agrakqpvif hgqltgnmdv aipqvpggrk vifdgsvnlp egtlsqdsgt
      661 lifqghpvih asisgsapvs lnqkdwenrq ftmktlslkd adfhlsrnas lnsdiksdns
      721 hitlgsdraf vdkndgtgny vipeegtsvp dtvndrsqye gnitlnhnsa ldigsrftgg
      781 idaydsavsi tspdvlltap gafagssltv hdgghltaln glfsdghiqa gkngkitlsg
      841 tpvkdtanqy apavyltdgy dltgdnaale itrgahasgd ihasaastvt igsdtpaela
      901 saetaasafa gsllegynaa fngaitggra dvsmhnalwt lggdsaihsl tvrnsrisse
      961 gdrtfrtltv nkldatgsdf vlrtdlknad kinvtekatg sdnslnvsfm nnpaqgqaln
     1021 iplvtapagt saemfkagtr vtgfsrvtpt lhvdtsggnt kwildgfkae adkaaaakad
     1081 sfmnagyknf mtevnnlnkr mgdlrdtngd agawarimsg agsadggysd nythvqvgfd
     1141 kkheldgvdl ftgvtmtytd ssadshafsg ktksvgggly asalfesgay idligkyihh
     1201 dndytgnfas lgtkhynths wyagaetgyr yhltedtfie pqaelvygav sgktfrwkdg
     1261 dmdlsmknrd fsplvgrtgv elgktfsgkd wsvtaragts wqfdllnnge tvlrdasgek
     1321 rikgekdsrm lfnvgmnaqi kdnmrfglef eksafgkynv dnavnanfry mf