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penicillin-insensitive murein endopeptidase [Escherichia coli].


LOCUS       WP_001043834             274 aa            linear   BCT 13-MAR-2021
ACCESSION   WP_001043834
VERSION     WP_001043834.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 274)
  AUTHORS   Marcyjaniak,M., Odintsov,S.G., Sabala,I. and Bochtler,M.
  TITLE     Peptidoglycan amidase MepA is a LAS metallopeptidase
  JOURNAL   J Biol Chem 279 (42), 43982-43989 (2004)
   PUBMED   15292190
REFERENCE   2  (residues 1 to 274)
  AUTHORS   Keck,W., van Leeuwen,A.M., Huber,M. and Goodell,E.W.
  TITLE     Cloning and characterization of mepA, the structural gene of the
            penicillin-insensitive murein endopeptidase from Escherichia coli
  JOURNAL   Mol Microbiol 4 (2), 209-219 (1990)
   PUBMED   2187143
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006947.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09429
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..274
                     /gene="mepA"
     Protein         1..274
                     /product="penicillin-insensitive murein endopeptidase"
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=30014
     Region          21..272
                     /region_name="mepA"
                     /note="penicillin-insensitive murein endopeptidase;
                     Reviewed; PRK09429"
                     /db_xref="CDD:236511"
ORIGIN      
        1 mnktaialla llassvslaa tpwqkitqpv pgsaqsigsf sngcivgadt lpiqsehyqv
       61 mrtdqrryfg hpdlvmfiqr lssqvsnlgm gtvligdmgm paggrfnggh ashqtgldvd
      121 iflqlpktrr tsaqllrpqa ldlvsrdgkh vvstlwkpei fsliklaaqd kdvtrifvnp
      181 aikqqlclda gtdrdwlrkv rpwfqhrahm hvrlrcpads lecedqplpp pgdgcgaelq
      241 swfeppkpgt tkpekktppp lppscqalld ehvi