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MULTISPECIES: type III secretion system effector NleA


LOCUS       WP_001025672             441 aa            linear   BCT 06-APR-2022
            [Enterobacteriaceae].
ACCESSION   WP_001025672
VERSION     WP_001025672.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 441)
  AUTHORS   Yen,H., Sugimoto,N. and Tobe,T.
  TITLE     Enteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3
            Inflammasome Activation
  JOURNAL   PLoS Pathog. 11 (9), e1005121 (2015)
   PUBMED   26332984
REFERENCE   2  (residues 1 to 441)
  AUTHORS   Creuzburg,K., Heeren,S., Lis,C.M., Kranz,M., Hensel,M. and
            Schmidt,H.
  TITLE     Genetic background and mobility of variants of the gene nleA in
            attaching and effacing Escherichia coli
  JOURNAL   Appl. Environ. Microbiol. 77 (24), 8705-8713 (2011)
   PUBMED   22003022
REFERENCE   3  (residues 1 to 441)
  AUTHORS   Creuzburg,K. and Schmidt,H.
  TITLE     Molecular characterization and distribution of genes encoding
            members of the type III effector nleA family among pathogenic
            Escherichia coli strains
  JOURNAL   J. Clin. Microbiol. 45 (8), 2498-2507 (2007)
   PUBMED   17553972
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000637
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..441
                     /gene="nleA"
     Protein         1..441
                     /product="type III secretion system effector NleA"
                     /calculated_mol_wt=47506
     Region          3..440
                     /region_name="NleA-like"
                     /note="bacterial effector protein NleA, and similar
                     proteins; cd21500"
                     /db_xref="CDD:412059"
ORIGIN      
        1 mniqptiqsg itsqnnqhhq teqipstqip qselplgcqa gfvvnipddi qqhapecget
       61 tallslikdk gllsgldeyi aphleegsig kktldmfglf nvtqmaleip ssvsgisgky
      121 gvqlnivkpd ihptsgnyfl qifplhdeig fnfkdlpgpl knalsnsnis ttavstiast
      181 gtsattstvt tepkdpipwf gltaqvvrnh gvelpivkte ngwklvgetp ltpdgpkany
      241 teewvirpge adfkygaspl qatlglefga hfkwdldnpn tkyavltnaa analgalggf
      301 avsrfastdp mlsphigamv gqaaghaiqy ntpglkpdti lwwagatlga adlnkaefev
      361 arftdypriw wharegaifp nkadiehatg adirameegi pvgqrhpnpe dvvidiesng
      421 lphhnpsnhv difdiiqetr v