MULTISPECIES: UDP-N-acetylmuramate dehydrogenase

LOCUS       WP_001016699             342 aa            linear   BCT 16-DEC-2020
            [Enterobacteriaceae].
ACCESSION   WP_001016699
VERSION     WP_001016699.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 342)
  AUTHORS   El Zoeiby,A., Sanschagrin,F. and Levesque,R.C.
  TITLE     Structure and function of the Mur enzymes: development of novel
            inhibitors
  JOURNAL   Mol. Microbiol. 47 (1), 1-12 (2003)
   PUBMED   12492849
REFERENCE   2  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     X-ray crystal structures of the S229A mutant and wild-type MurB in
            the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine
            at 1.8-A resolution
  JOURNAL   Biochemistry 36 (4), 806-811 (1997)
   PUBMED   9020778
REFERENCE   3  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     The structure of the substrate-free form of MurB, an essential
            enzyme for the synthesis of bacterial cell walls
  JOURNAL   Structure 4 (1), 47-54 (1996)
   PUBMED   8805513
REFERENCE   4  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     Crystallization and preliminary X-ray crystallographic studies of
            UDP-N-acetylenolpyruvylglucosamine reductase
  JOURNAL   Protein Sci. 3 (7), 1125-1127 (1994)
   PUBMED   7920261
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF000755.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00046
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..342
                     /gene="murB"
     Protein         1..342
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /EC_number="1.3.1.98"
                     /GO_function="GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /calculated_mol_wt=37720
     Region          1..329
                     /region_name="murB"
                     /note="UDP-N-acetylmuramate dehydrogenase; PRK00046"
                     /db_xref="CDD:234593"
ORIGIN      
        1 mnhslkpwnt fgidhnaqhi vcaedeqqll nawqyataeg qpvlilgegs nvlfledyrg
       61 tviinrikgi eihdepdawy lhvgagenwh rlvkytlqeg mpglenlali pgcvgsspiq
      121 nigaygvelq rvcayvdsve latgkqvrlt akecrfgyrd sifkheyqdr faivavglrl
      181 pkewqpvlty gdltrldptt vtpqqvfnav chmrttklpd pkvngnagsf fknpvvsaet
      241 akallsqfpt apnypqadgs vklaagwlid qcqlkgmqig gaavhrqqal vlinednaks
      301 edvvqlahhv rqkvgekfnv wlepevrfig asgevsavet is