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LOCUS WP_001016661 342 aa linear BCT 11-DEC-2019 ACCESSION WP_001016661 VERSION WP_001016661.1 KEYWORDS RefSeq. SOURCE Escherichia coli ORGANISM Escherichia coli Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 342) AUTHORS El Zoeiby,A., Sanschagrin,F. and Levesque,R.C. TITLE Structure and function of the Mur enzymes: development of novel inhibitors JOURNAL Mol. Microbiol. 47 (1), 1-12 (2003) PUBMED 12492849 REFERENCE 2 (residues 1 to 342) AUTHORS Benson,T.E., Walsh,C.T. and Hogle,J.M. TITLE X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution JOURNAL Biochemistry 36 (4), 806-811 (1997) PUBMED 9020778 REFERENCE 3 (residues 1 to 342) AUTHORS Benson,T.E., Walsh,C.T. and Hogle,J.M. TITLE The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls JOURNAL Structure 4 (1), 47-54 (1996) PUBMED 8805513 REFERENCE 4 (residues 1 to 342) AUTHORS Benson,T.E., Walsh,C.T. and Hogle,J.M. TITLE Crystallization and preliminary X-ray crystallographic studies of UDP-N-acetylenolpyruvylglucosamine reductase JOURNAL Protein Sci. 3 (7), 1125-1127 (1994) PUBMED 7920261 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF000755.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK00046 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..342 /organism="Escherichia coli" /db_xref="taxon:562" gene 1..342 /gene="murB" Protein 1..342 /product="UDP-N-acetylmuramate dehydrogenase" /EC_number="1.3.1.98" /GO_function="GO:0008762 - UDP-N-acetylmuramate dehydrogenase activity [Evidence IEA]" /GO_function="GO:0071949 - FAD binding [Evidence IEA]" /calculated_mol_wt=37757 Region 1..329 /region_name="murB" /note="UDP-N-acetylmuramate dehydrogenase; PRK00046" /db_xref="CDD:234593" ORIGIN 1 mnhslkpwnt fgidhnaqhi vcaedeqqll nawqhataeg qpvlilgegs nvlfledyrg 61 tviinrikgi eihdepdawy lhvgagenwh rlvkytlqeg mpglenlali pgcvgsspiq 121 nigaygvelq rvcayvdcve latgkqvrlt akecrfgyrd sifkheyqdr faivavglrl 181 pkewqpvlty gdltrldptt vtpqqvfdav chmrttklpd pkvngnagsf fknpvvsaet 241 akallsqfpt apnypqadgs vklaagwlid qcqlkgmqmg gvavhrqqal vlinednaks 301 edvvqlahhv rqkvgekfnv wlepevrfig asgevsavet is