Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS WP_001011000 316 aa linear BCT 11-DEC-2019 [Enterobacteriaceae]. ACCESSION WP_001011000 VERSION WP_001011000.1 KEYWORDS RefSeq. SOURCE Enterobacteriaceae ORGANISM Enterobacteriaceae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales. REFERENCE 1 (residues 1 to 316) AUTHORS Stec,E., Witkowska-Zimny,M., Hryniewicz,M.M., Neumann,P., Wilkinson,A.J., Brzozowski,A.M., Verma,C.S., Zaim,J., Wysocki,S. and Bujacz,G.D. TITLE Structural basis of the sulphate starvation response in E. coli: crystal structure and mutational analysis of the cofactor-binding domain of the Cbl transcriptional regulator JOURNAL J. Mol. Biol. 364 (3), 309-322 (2006) PUBMED 17010379 REFERENCE 2 (residues 1 to 316) AUTHORS Lochowska,A., Iwanicka-Nowicka,R., Zaim,J., Witkowska-Zimny,M., Bolewska,K. and Hryniewicz,M.M. TITLE Identification of activating region (AR) of Escherichia coli LysR-type transcription factor CysB and CysB contact site on RNA polymerase alpha subunit at the cysP promoter JOURNAL Mol. Microbiol. 53 (3), 791-806 (2004) PUBMED 15255893 REFERENCE 3 (residues 1 to 316) AUTHORS Jovanovic,M., Lilic,M., Savic,D.J. and Jovanovic,G. TITLE The LysR-type transcriptional regulator CysB controls the repression of hslJ transcription in Escherichia coli JOURNAL Microbiology (Reading, Engl.) 149 (Pt 12), 3449-3459 (2003) PUBMED 14663078 REFERENCE 4 (residues 1 to 316) AUTHORS Bykowski,T., van der Ploeg,J.R., Iwanicka-Nowicka,R. and Hryniewicz,M.M. TITLE The switch from inorganic to organic sulphur assimilation in Escherichia coli: adenosine 5'-phosphosulphate (APS) as a signalling molecule for sulphate excess JOURNAL Mol. Microbiol. 43 (5), 1347-1358 (2002) PUBMED 11918818 REFERENCE 5 (residues 1 to 316) AUTHORS Lochowska,A., Iwanicka-Nowicka,R., Plochocka,D. and Hryniewicz,M.M. TITLE Functional dissection of the LysR-type CysB transcriptional regulator. Regions important for DNA binding, inducer response, oligomerization, and positive control JOURNAL J. Biol. Chem. 276 (3), 2098-2107 (2001) PUBMED 11038360 REFERENCE 6 (residues 1 to 316) AUTHORS Tyrrell,R., Verschueren,K.H., Dodson,E.J., Murshudov,G.N., Addy,C. and Wilkinson,A.J. TITLE The structure of the cofactor-binding fragment of the LysR family member, CysB: a familiar fold with a surprising subunit arrangement JOURNAL Structure 5 (8), 1017-1032 (1997) PUBMED 9309218 REFERENCE 7 (residues 1 to 316) AUTHORS Iwanicka-Nowicka,R. and Hryniewicz,M.M. TITLE A new gene, cbl, encoding a member of the LysR family of transcriptional regulators belongs to Escherichia coli cys regulon JOURNAL Gene 166 (1), 11-17 (1995) PUBMED 8529872 REFERENCE 8 (residues 1 to 316) AUTHORS Miller,B.E. and Kredich,N.M. TITLE Purification of the cysB protein from Salmonella typhimurium JOURNAL J. Biol. Chem. 262 (13), 6006-6009 (1987) PUBMED 3032953 REFERENCE 9 (residues 1 to 316) AUTHORS Bielinska,A. and Hulanicka,D. TITLE Regulation of the cysB gene expression in Escherichia coli JOURNAL Acta Biochim. Pol. 33 (2), 133-137 (1986) PUBMED 3094306 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF009324.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK12679 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..316 /organism="Enterobacteriaceae" /db_xref="taxon:543" gene 1..316 /gene="cbl" Protein 1..316 /product="HTH-type transcriptional regulator Cbl" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_process="GO:0006355 - regulation of transcription, DNA-templated [Evidence IEA]" /calculated_mol_wt=35788 Region 1..316 /region_name="cbl" /note="HTH-type transcriptional regulator Cbl; PRK12679" /db_xref="CDD:183676" ORIGIN 1 mnfqqlkiir eaarqdynlt evanmlftsq sgvsrhirel edelgieifv rrgkrllgmt 61 epgkallvia erilneasnv rrladlftnd tsgvltiatt htqaryslpe vikafrelfp 121 evrleliqgt pqeiatllhn geadigiase rlsndpqlva fpwfrwhhsl lvphdhpltq 181 itpltlesia kwplityrqg itgrsridda farkglladi ilsaqdsdvi ktyvalglgi 241 glvaeqssge qeeknlirld trhlfdantv wlglkrgqlq rnyvwrflel cnaglsvedi 301 krqvmensee eidyqi