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MULTISPECIES: HTH-type transcriptional regulator Cbl


LOCUS       WP_001011000             316 aa            linear   BCT 11-DEC-2019
            [Enterobacteriaceae].
ACCESSION   WP_001011000
VERSION     WP_001011000.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 316)
  AUTHORS   Stec,E., Witkowska-Zimny,M., Hryniewicz,M.M., Neumann,P.,
            Wilkinson,A.J., Brzozowski,A.M., Verma,C.S., Zaim,J., Wysocki,S.
            and Bujacz,G.D.
  TITLE     Structural basis of the sulphate starvation response in E. coli:
            crystal structure and mutational analysis of the cofactor-binding
            domain of the Cbl transcriptional regulator
  JOURNAL   J. Mol. Biol. 364 (3), 309-322 (2006)
   PUBMED   17010379
REFERENCE   2  (residues 1 to 316)
  AUTHORS   Lochowska,A., Iwanicka-Nowicka,R., Zaim,J., Witkowska-Zimny,M.,
            Bolewska,K. and Hryniewicz,M.M.
  TITLE     Identification of activating region (AR) of Escherichia coli
            LysR-type transcription factor CysB and CysB contact site on RNA
            polymerase alpha subunit at the cysP promoter
  JOURNAL   Mol. Microbiol. 53 (3), 791-806 (2004)
   PUBMED   15255893
REFERENCE   3  (residues 1 to 316)
  AUTHORS   Jovanovic,M., Lilic,M., Savic,D.J. and Jovanovic,G.
  TITLE     The LysR-type transcriptional regulator CysB controls the
            repression of hslJ transcription in Escherichia coli
  JOURNAL   Microbiology (Reading, Engl.) 149 (Pt 12), 3449-3459 (2003)
   PUBMED   14663078
REFERENCE   4  (residues 1 to 316)
  AUTHORS   Bykowski,T., van der Ploeg,J.R., Iwanicka-Nowicka,R. and
            Hryniewicz,M.M.
  TITLE     The switch from inorganic to organic sulphur assimilation in
            Escherichia coli: adenosine 5'-phosphosulphate (APS) as a
            signalling molecule for sulphate excess
  JOURNAL   Mol. Microbiol. 43 (5), 1347-1358 (2002)
   PUBMED   11918818
REFERENCE   5  (residues 1 to 316)
  AUTHORS   Lochowska,A., Iwanicka-Nowicka,R., Plochocka,D. and Hryniewicz,M.M.
  TITLE     Functional dissection of the LysR-type CysB transcriptional
            regulator. Regions important for DNA binding, inducer response,
            oligomerization, and positive control
  JOURNAL   J. Biol. Chem. 276 (3), 2098-2107 (2001)
   PUBMED   11038360
REFERENCE   6  (residues 1 to 316)
  AUTHORS   Tyrrell,R., Verschueren,K.H., Dodson,E.J., Murshudov,G.N., Addy,C.
            and Wilkinson,A.J.
  TITLE     The structure of the cofactor-binding fragment of the LysR family
            member, CysB: a familiar fold with a surprising subunit arrangement
  JOURNAL   Structure 5 (8), 1017-1032 (1997)
   PUBMED   9309218
REFERENCE   7  (residues 1 to 316)
  AUTHORS   Iwanicka-Nowicka,R. and Hryniewicz,M.M.
  TITLE     A new gene, cbl, encoding a member of the LysR family of
            transcriptional regulators belongs to Escherichia coli cys regulon
  JOURNAL   Gene 166 (1), 11-17 (1995)
   PUBMED   8529872
REFERENCE   8  (residues 1 to 316)
  AUTHORS   Miller,B.E. and Kredich,N.M.
  TITLE     Purification of the cysB protein from Salmonella typhimurium
  JOURNAL   J. Biol. Chem. 262 (13), 6006-6009 (1987)
   PUBMED   3032953
REFERENCE   9  (residues 1 to 316)
  AUTHORS   Bielinska,A. and Hulanicka,D.
  TITLE     Regulation of the cysB gene expression in Escherichia coli
  JOURNAL   Acta Biochim. Pol. 33 (2), 133-137 (1986)
   PUBMED   3094306
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009324.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK12679
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..316
                     /gene="cbl"
     Protein         1..316
                     /product="HTH-type transcriptional regulator Cbl"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /calculated_mol_wt=35788
     Region          1..316
                     /region_name="cbl"
                     /note="HTH-type transcriptional regulator Cbl; PRK12679"
                     /db_xref="CDD:183676"
ORIGIN      
        1 mnfqqlkiir eaarqdynlt evanmlftsq sgvsrhirel edelgieifv rrgkrllgmt
       61 epgkallvia erilneasnv rrladlftnd tsgvltiatt htqaryslpe vikafrelfp
      121 evrleliqgt pqeiatllhn geadigiase rlsndpqlva fpwfrwhhsl lvphdhpltq
      181 itpltlesia kwplityrqg itgrsridda farkglladi ilsaqdsdvi ktyvalglgi
      241 glvaeqssge qeeknlirld trhlfdantv wlglkrgqlq rnyvwrflel cnaglsvedi
      301 krqvmensee eidyqi