MULTISPECIES:

LOCUS       WP_000999466             331 aa            linear   BCT 10-AUG-2020
            N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,
            octacis-undecaprenol 4-epimerase [Enterobacteriaceae].
ACCESSION   WP_000999466
VERSION     WP_000999466.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 331)
  AUTHORS   Cunneen,M.M., Liu,B., Wang,L. and Reeves,P.R.
  TITLE     Biosynthesis of UDP-GlcNAc, UndPP-GlcNAc and UDP-GlcNAcA involves
            three easily distinguished 4-epimerase enzymes, Gne, Gnu and GnaB
  JOURNAL   PLoS ONE 8 (6), e67646 (2013)
   PUBMED   23799153
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 331)
  AUTHORS   Rush,J.S., Alaimo,C., Robbiani,R., Wacker,M. and Waechter,C.J.
  TITLE     A novel epimerase that converts GlcNAc-P-P-undecaprenol to
            GalNAc-P-P-undecaprenol in Escherichia coli O157
  JOURNAL   J. Biol. Chem. 285 (3), 1671-1680 (2010)
   PUBMED   19923219
REFERENCE   3  (residues 1 to 331)
  AUTHORS   Wang,L., Huskic,S., Cisterne,A., Rothemund,D. and Reeves,P.R.
  TITLE     The O-antigen gene cluster of Escherichia coli O55:H7 and
            identification of a new UDP-GlcNAc C4 epimerase gene
  JOURNAL   J. Bacteriol. 184 (10), 2620-2625 (2002)
   PUBMED   11976290
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012691
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..331
                     /product="N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,
                     octacis-undecaprenol 4-epimerase"
                     /EC_number="5.1.3.26"
                     /calculated_mol_wt=37011
     Region          3..310
                     /region_name="Gne_like_SDR_e"
                     /note="Escherichia coli Gne (a
                     nucleoside-diphosphate-sugar 4-epimerase)-like, extended
                     (e) SDRs; cd05238"
                     /db_xref="CDD:187549"
     Site            order(9,11..14,30..32,68..70,84,107..109,132,136,160..163)
                     /site_type="other"
                     /note="putative NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187549"
     Site            order(85,109,132,136)
                     /site_type="active"
                     /db_xref="CDD:187549"
     Site            order(109,132,162,182,192)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:187549"
ORIGIN      
        1 mndnvlliga sgfvgtrlle taiadfnikn ldkqqshfyp eitqigdvrd qqaldqalag
       61 fdtvvllaae hrddvsptsl yydvnvqgtr nvlaamekng vkniiftssv avyglnkhnp
      121 denhphdpfn hygkskwqae evlrewynka ptersltiir ptvifgernr gnvynllkqi
      181 aggkfmmvga gtnyksmayv gnivefikyk lknvaagyev ynyvdkpdln mnqlvaeveq
      241 slnkkipsmh lpyplgmlgg ycfdilskit gkkyavssvr vkkfcattqf datkvhssgf
      301 vapytlsqgl drtlqyefvh akkdditfvs e