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type II toxin-antitoxin system PemK/MazF family toxin [Escherichia


LOCUS       WP_000996692             149 aa            linear   BCT 01-MAR-2025
            coli].
ACCESSION   WP_000996692
VERSION     WP_000996692.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 149)
  AUTHORS   Yamaguchi,Y. and Inouye,M.
  TITLE     Regulation of growth and death in Escherichia coli by
            toxin-antitoxin systems
  JOURNAL   Nat Rev Microbiol 9 (11), 779-790 (2011)
   PUBMED   21927020
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 149)
  AUTHORS   Yamaguchi,Y., Park,J.H. and Inouye,M.
  TITLE     Toxin-antitoxin systems in bacteria and archaea
  JOURNAL   Annu Rev Genet 45, 61-79 (2011)
   PUBMED   22060041
REFERENCE   3  (residues 1 to 149)
  AUTHORS   Masuda,Y., Miyakawa,K., Nishimura,Y. and Ohtsubo,E.
  TITLE     chpA and chpB, Escherichia coli chromosomal homologs of the pem
            locus responsible for stable maintenance of plasmid R100
  JOURNAL   J Bacteriol 175 (21), 6850-6856 (1993)
   PUBMED   8226627
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF014505.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF02452.23
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..149
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..149
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=16825
     Region          1..148
                     /region_name="YifN"
                     /note="Uncharacterized conserved protein YifN, PemK
                     superfamily [Function unknown]; COG3692"
                     /db_xref="CDD:442907"
ORIGIN      
        1 mainfspkvg eilecnfgny pvsqngpfst tyydgrippe miknrlvvvl ngkingnafi
       61 vvplsttrdh dklkrgmhve iasnvindlq ffdqqirwak tdlvqqvsrn rlnrartyrg
      121 ylnqclphel vadiqravik sinaislin