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MULTISPECIES: restriction endonuclease [Enterobacterales].


LOCUS       WP_000996055             331 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_000996055
VERSION     WP_000996055.1
KEYWORDS    RefSeq.
SOURCE      Enterobacterales
  ORGANISM  Enterobacterales
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria.
REFERENCE   1  (residues 1 to 331)
  AUTHORS   Kosinski,J., Feder,M. and Bujnicki,J.M.
  TITLE     The PD-(D/E)XK superfamily revisited: identification of new members
            among proteins involved in DNA metabolism and functional
            predictions for domains of (hitherto) unknown function
  JOURNAL   BMC Bioinformatics 6, 172 (2005)
   PUBMED   16011798
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 331)
  AUTHORS   Kinch,L.N., Ginalski,K., Rychlewski,L. and Grishin,N.V.
  TITLE     Identification of novel restriction endonuclease-like fold families
            among hypothetical proteins
  JOURNAL   Nucleic Acids Res 33 (11), 3598-3605 (2005)
   PUBMED   15972856
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 331)
  AUTHORS   Bujnicki,J.M. and Rychlewski,L.
  TITLE     Identification of a PD-(D/E)XK-like domain with a novel
            configuration of the endonuclease active site in the
            methyl-directed restriction enzyme Mrr and its homologs
  JOURNAL   Gene 267 (2), 183-191 (2001)
   PUBMED   11313145
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11447960
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Enterobacterales"
                     /db_xref="taxon:91347"
     Protein         1..331
                     /product="restriction endonuclease"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /calculated_mol_wt=37612
     Region          184..300
                     /region_name="Mrr"
                     /note="Restriction endonuclease Mrr [Defense mechanisms];
                     COG1715"
                     /db_xref="CDD:441321"
ORIGIN      
        1 mndapsdiif hyppelfnll vdvvpllnrs kqdvlvffrg agvpdnitsd iavhlraapk
       61 dvnkyqmvrt vlerlnakge halrerrevl rrvvdfanfd scwpadqlka kglvasirev
      121 vnqkdaftrm nnareeerqt rlaesqriaa ekrdrsyrie nakqglyklf gttataqerg
      181 klletalnnl fqaygvlirk sfhlvgeage giveqidgii elsgvlyfve mkwyrnpvgk
      241 peisehlvrl msraevrgif isasdytepa iltareflqh kvvvlstlhe ivrlleqqdd
      301 lsefftkkvq aaqihknpyf cphdsqaqga l