heme anaerobic degradation radical SAM methyltransferase ChuW/HutW

LOCUS       WP_000993317             445 aa            linear   BCT 29-APR-2021
            [Escherichia coli].
ACCESSION   WP_000993317
VERSION     WP_000993317.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 445)
  AUTHORS   LaMattina,J.W., Nix,D.B. and Lanzilotta,W.N.
  TITLE     Radical new paradigm for heme degradation in Escherichia coli
            O157:H7
  JOURNAL   Proc Natl Acad Sci U S A 113 (43), 12138-12143 (2016)
   PUBMED   27791000
REFERENCE   2  (residues 1 to 445)
  AUTHORS   Wyckoff,E.E., Schmitt,M., Wilks,A. and Payne,S.M.
  TITLE     HutZ is required for efficient heme utilization in Vibrio cholerae
  JOURNAL   J Bacteriol 186 (13), 4142-4151 (2004)
   PUBMED   15205415
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR04107.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..445
                     /gene="hutW"
     Protein         1..445
                     /product="heme anaerobic degradation radical SAM
                     methyltransferase ChuW/HutW"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /calculated_mol_wt=49418
     Region          19..433
                     /region_name="rSAM_HutW"
                     /note="putative heme utilization radical SAM enzyme HutW;
                     TIGR04107"
                     /db_xref="CDD:274985"
ORIGIN      
        1 mnanntldlt phfaldgdqp fkdrrammpf rgaipvakeq laqtwqemin qtasprkrlv
       61 ylhipfcath ctfcgfyqnr fnedacahyt dalireieme adsvlhqsap ihavyfgggt
      121 psalsahdla riittlrekl plapdceiti egrvlnfdae ridacldaga nrfsigiqsf
      181 nskirkkmar tsdgptaiaf meslvkrdra avvcdllfgl pgqdaqtwge dlaiardigl
      241 dgvdlyalnv lsntplgkav engrttvpsp aerrdlylqg cdfmddagwr cisnshwgrt
      301 trernlynll ikqgadclaf gsgaggsing yswmnernlq twhesvaagk kplmlimrna
      361 ernaqwrhtl qsgvetarvp ldeltphaek lapllaqwhq kglsrdastc lrltnegrfw
      421 asnilqslne liqvlnapai mrekp