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LOCUS WP_000986522 224 aa linear BCT 20-DEC-2020 ACCESSION WP_000986522 VERSION WP_000986522.1 KEYWORDS RefSeq. SOURCE Salmonella enterica ORGANISM Salmonella enterica Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella. REFERENCE 1 (residues 1 to 224) AUTHORS Kroger,C., Dillon,S.C., Cameron,A.D., Papenfort,K., Sivasankaran,S.K., Hokamp,K., Chao,Y., Sittka,A., Hebrard,M., Handler,K., Colgan,A., Leekitcharoenphon,P., Langridge,G.C., Lohan,A.J., Loftus,B., Lucchini,S., Ussery,D.W., Dorman,C.J., Thomson,N.R., Vogel,J. and Hinton,J.C. TITLE The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium JOURNAL Proc. Natl. Acad. Sci. U.S.A. 109 (20), E1277-E1286 (2012) PUBMED 22538806 REFERENCE 2 (residues 1 to 224) AUTHORS Luo,Y., Kong,Q., Yang,J., Golden,G., Wanda,S.Y., Jensen,R.V., Ernst,P.B. and Curtiss,R. 3rd. TITLE Complete genome sequence of the universal killer Salmonella enterica Serovar Typhimurium UK-1 (ATCC 68169) JOURNAL J. Bacteriol. 193 (15), 4035-4036 (2011) PUBMED 21622747 REFERENCE 3 (residues 1 to 224) AUTHORS Bader,M.W., Sanowar,S., Daley,M.E., Schneider,A.R., Cho,U., Xu,W., Klevit,R.E., Le Moual,H. and Miller,S.I. TITLE Recognition of antimicrobial peptides by a bacterial sensor kinase JOURNAL Cell 122 (3), 461-472 (2005) PUBMED 16096064 REFERENCE 4 (residues 1 to 224) AUTHORS Bijlsma,J.J. and Groisman,E.A. TITLE The PhoP/PhoQ system controls the intramacrophage type three secretion system of Salmonella enterica JOURNAL Mol. Microbiol. 57 (1), 85-96 (2005) PUBMED 15948951 REFERENCE 5 (residues 1 to 224) AUTHORS Zwir,I., Shin,D., Kato,A., Nishino,K., Latifi,T., Solomon,F., Hare,J.M., Huang,H. and Groisman,E.A. TITLE Dissecting the PhoP regulatory network of Escherichia coli and Salmonella enterica JOURNAL Proc. Natl. Acad. Sci. U.S.A. 102 (8), 2862-2867 (2005) PUBMED 15703297 REFERENCE 6 (residues 1 to 224) AUTHORS Tierrez,A. and Garcia-del Portillo,F. TITLE The Salmonella membrane protein IgaA modulates the activity of the RcsC-YojN-RcsB and PhoP-PhoQ regulons JOURNAL J. Bacteriol. 186 (22), 7481-7489 (2004) PUBMED 15516559 REFERENCE 7 (residues 1 to 224) AUTHORS Lejona,S., Castelli,M.E., Cabeza,M.L., Kenney,L.J., Garcia Vescovi,E. and Soncini,F.C. TITLE PhoP can activate its target genes in a PhoQ-independent manner JOURNAL J. Bacteriol. 186 (8), 2476-2480 (2004) PUBMED 15060051 REFERENCE 8 (residues 1 to 224) AUTHORS Bader,M.W., Navarre,W.W., Shiau,W., Nikaido,H., Frye,J.G., McClelland,M., Fang,F.C. and Miller,S.I. TITLE Regulation of Salmonella typhimurium virulence gene expression by cationic antimicrobial peptides JOURNAL Mol. Microbiol. 50 (1), 219-230 (2003) PUBMED 14507376 REFERENCE 9 (residues 1 to 224) AUTHORS Cano,D.A., Martinez-Moya,M., Pucciarelli,M.G., Groisman,E.A., Casadesus,J. and Garcia-Del Portillo,F. TITLE Salmonella enterica serovar Typhimurium response involved in attenuation of pathogen intracellular proliferation JOURNAL Infect. Immun. 69 (10), 6463-6474 (2001) PUBMED 11553591 REFERENCE 10 (residues 1 to 224) AUTHORS Kox,L.F., Wosten,M.M. and Groisman,E.A. TITLE A small protein that mediates the activation of a two-component system by another two-component system JOURNAL EMBO J. 19 (8), 1861-1872 (2000) PUBMED 10775270 REFERENCE 11 (residues 1 to 224) AUTHORS van Velkinburgh,J.C. and Gunn,J.S. TITLE PhoP-PhoQ-regulated loci are required for enhanced bile resistance in Salmonella spp JOURNAL Infect. Immun. 67 (4), 1614-1622 (1999) PUBMED 10084994 REFERENCE 12 (residues 1 to 224) AUTHORS Baker,S.J., Gunn,J.S. and Morona,R. TITLE The Salmonella typhi melittin resistance gene pqaB affects intracellular growth in PMA-differentiated U937 cells, polymyxin B resistance and lipopolysaccharide JOURNAL Microbiology (Reading, Engl.) 145 (Pt 2), 367-378 (1999) PUBMED 10075419 REFERENCE 13 (residues 1 to 224) AUTHORS Bearson,B.L., Wilson,L. and Foster,J.W. TITLE A low pH-inducible, PhoPQ-dependent acid tolerance response protects Salmonella typhimurium against inorganic acid stress JOURNAL J. Bacteriol. 180 (9), 2409-2417 (1998) PUBMED 9573193 REMARK Erratum:[J Bacteriol 1998 Jul;180(14):3734] REFERENCE 14 (residues 1 to 224) AUTHORS Garcia Vescovi,E., Soncini,F.C. and Groisman,E.A. TITLE Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence JOURNAL Cell 84 (1), 165-174 (1996) PUBMED 8548821 REFERENCE 15 (residues 1 to 224) AUTHORS Soncini,F.C., Vescovi,E.G. and Groisman,E.A. TITLE Transcriptional autoregulation of the Salmonella typhimurium phoPQ operon JOURNAL J. Bacteriol. 177 (15), 4364-4371 (1995) PUBMED 7543474 REFERENCE 16 (residues 1 to 224) AUTHORS Behlau,I. and Miller,S.I. TITLE A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells JOURNAL J. Bacteriol. 175 (14), 4475-4484 (1993) PUBMED 8392513 REFERENCE 17 (residues 1 to 224) AUTHORS Groisman,E.A., Chiao,E., Lipps,C.J. and Heffron,F. TITLE Salmonella typhimurium phoP virulence gene is a transcriptional regulator JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (18), 7077-7081 (1989) PUBMED 2674945 REFERENCE 18 (residues 1 to 224) AUTHORS Miller,S.I., Kukral,A.M. and Mekalanos,J.J. TITLE A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (13), 5054-5058 (1989) PUBMED 2544889 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: BlastRule Evidence Accession :: NBR000714 Evidence Source :: NCBI ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..224 /organism="Salmonella enterica" /db_xref="taxon:28901" gene 1..224 /gene="phoP" Protein 1..224 /product="two-component system response regulator PhoP" /calculated_mol_wt=25502 Region 2..224 /region_name="PRK10816" /note="two-component system response regulator PhoP" /db_xref="CDD:182755" ORIGIN 1 mmrvlvvedn allrhhlkvq lqdsghqvda aedareadyy lnehlpdiai vdlglpdedg 61 lslirrwrss dvslpvlvlt aregwqdkve vlssgaddyv tkpfhieevm armqalmrrn 121 sglasqvini ppfqvdlsrr elsvneevik ltafeytime tlirnngkvv skdslmlqly 181 pdaelresht idvlmgrlrk kiqaqyphdv ittvrgqgyl felr