diaminopimelate epimerase [Shigella flexneri].

LOCUS       WP_000983200             275 aa            linear   BCT 19-MAY-2021
ACCESSION   WP_000983200
VERSION     WP_000983200.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 275)
  AUTHORS   Hor,L., Dobson,R.C., Downton,M.T., Wagner,J., Hutton,C.A. and
            Perugini,M.A.
  TITLE     Dimerization of bacterial diaminopimelate epimerase is essential
            for catalysis
  JOURNAL   J Biol Chem 288 (13), 9238-9248 (2013)
   PUBMED   23426375
REFERENCE   2  (residues 1 to 275)
  AUTHORS   Usha,V., Dover,L.G., Roper,D.L. and Besra,G.S.
  TITLE     Characterization of Mycobacterium tuberculosis diaminopimelic acid
            epimerase: paired cysteine residues are crucial for racemization
  JOURNAL   FEMS Microbiol Lett 280 (1), 57-63 (2008)
   PUBMED   18269631
REFERENCE   3  (residues 1 to 275)
  AUTHORS   Koo,C.W. and Blanchard,J.S.
  TITLE     Chemical mechanism of Haemophilus influenzae diaminopimelate
            epimerase
  JOURNAL   Biochemistry 38 (14), 4416-4422 (1999)
   PUBMED   10194362
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00652.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..275
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..275
                     /gene="dapF"
     Protein         1..275
                     /product="diaminopimelate epimerase"
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=30253
     Region          1..275
                     /region_name="DapF"
                     /note="Diaminopimelate epimerase [Amino acid transport and
                     metabolism]; COG0253"
                     /db_xref="CDD:440023"
ORIGIN      
        1 mmqfskmhgl gndfmvvdav tqnvffspel irrladrhlg vgfdqllvve ppydpeldfh
       61 yrifnadgse vaqcgngarc farfvrlkgl tnkrdirvst angrmvltvt dddlvrvnmg
      121 epnfepsavp frankaekty imraaeqtil cgvvsmgnph cviqvddvdt aavetlgpvl
      181 esherfpera nigfmqvvkr ehirlrvyer gagetqacgs gacaavavgi qqglldeevr
      241 velpggrldi awkgpghply mtgpavhvyd gfihl