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MULTISPECIES: itaconate CoA-transferase RipA/Ict [Salmonella].


LOCUS       WP_000982337             441 aa            linear   BCT 21-DEC-2020
ACCESSION   WP_000982337
VERSION     WP_000982337.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 441)
  AUTHORS   Hersch,S.J. and Navarre,W.W.
  TITLE     The Salmonella LysR Family Regulator RipR Activates the
            SPI-13-Encoded Itaconate Degradation Cluster
  JOURNAL   Infect Immun 88 (10), e00303-20 (2020)
   PUBMED   32719152
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 441)
  AUTHORS   Sasikaran,J., Ziemski,M., Zadora,P.K., Fleig,A. and Berg,I.A.
  TITLE     Bacterial itaconate degradation promotes pathogenicity
  JOURNAL   Nat Chem Biol 10 (5), 371-377 (2014)
   PUBMED   24657929
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            Transfers CoA from succinate to itaconate.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013578
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..441
                     /gene="ripA"
                     /gene_synonym="ict"
     Protein         1..441
                     /product="itaconate CoA-transferase RipA/Ict"
                     /EC_number="2.8.3.-"
                     /calculated_mol_wt=48291
     Region          8..439
                     /region_name="ACH1"
                     /note="Propionyl CoA:succinate CoA transferase [Energy
                     production and conversion]; COG0427"
                     /db_xref="CDD:440196"
ORIGIN      
        1 mmnvnavyae kcvtpdeavt litsgshlsm gmfaaeppal lnalakrakr geindlrvyc
       61 yetasiagnt ifryelsdyi hlysmfitgi eralirqgie ssgrkivnyv psnfhqatrl
      121 laddigidtf ihtvspmdky gyfnfgtgnd ystriartak klivevnkym prvhgegaai
      181 hiseidaive nhvplielpi rtavaediai sqiiaslvpd gaclqmgvga lpelicnalk
      241 ehndlgvhte alnpglvsli qqgvvtnqrk nidrgmsvft famgqkdmyd ylndnpsffs
      301 rpvdyvndpg iiaqnenvvs inatlqidlt gacnseyllg hqysasggql dfvrgayask
      361 ggrsiittrs taandtisri vprlegpvtt prtdthwivt efgsvnlkgl ssteralsii
      421 elahpnfrqq lrvdakkmhl i