MULTISPECIES: (2E,6E)-farnesyl-diphosphate-specific

LOCUS       WP_000979579             253 aa            linear   BCT 17-MAY-2022
            ditrans,polycis-undecaprenyl-diphosphate synthase
            [Enterobacteriaceae].
ACCESSION   WP_000979579
VERSION     WP_000979579.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 253)
  AUTHORS   Chang,S.Y., Ko,T.P., Chen,A.P., Wang,A.H. and Liang,P.H.
  TITLE     Substrate binding mode and reaction mechanism of undecaprenyl
            pyrophosphate synthase deduced from crystallographic studies
  JOURNAL   Protein Sci 13 (4), 971-978 (2004)
   PUBMED   15044730
REFERENCE   2  (residues 1 to 253)
  AUTHORS   Chang,S.Y., Ko,T.P., Liang,P.H. and Wang,A.H.
  TITLE     Catalytic mechanism revealed by the crystal structure of
            undecaprenyl pyrophosphate synthase in complex with sulfate,
            magnesium, and triton
  JOURNAL   J Biol Chem 278 (31), 29298-29307 (2003)
   PUBMED   12756244
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007596.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10240
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..253
                     /gene="ispU"
                     /gene_synonym="uppS"
     Protein         1..253
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /GO_function="GO:0002094 - polyprenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008834 -
                     di-trans,poly-cis-decaprenylcistransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0043164 - Gram-negative-bacterium-type
                     cell wall biogenesis [Evidence IEA]"
                     /calculated_mol_wt=28313
     Region          25..253
                     /region_name="PRK10240"
                     /note="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /db_xref="CDD:182326"
     Site            order(25..30,39,43,47,50,69,77,81,88..89,92,141,194,200,
                     202)
                     /site_type="active"
                     /db_xref="CDD:259850"
     Site            order(148..149,151..152,155..156,172..174,177,188,
                     199..203,206..208,210..214,216)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:259850"
ORIGIN      
        1 mmlsatqpls eklpahgcrh vaiimdgngr wakkqgkira fghkagaksv rravsfaann
       61 giealtlyaf ssenwnrpaq evsalmelfv waldsevksl hrhnvrlrii gdtsrfnsrl
      121 qerirkseal tagntgltln iaanyggrwd ivqgvrqlae kvqqgnlqpd qideemlnqh
      181 vcmhelapvd lvirtggehr isnfllwqia yaelyftdvl wpdfdeqdfe galnafanre
      241 rrfggtepgd eta