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MULTISPECIES: multifunctional D-malate/3-isopropylmalate/tartarate


LOCUS       WP_000978495             361 aa            linear   BCT 10-JUL-2019
            dehydrogenase [Enterobacteriaceae].
ACCESSION   WP_000978495
VERSION     WP_000978495.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 361)
  AUTHORS   Vorobieva,A.A., Khan,M.S. and Soumillion,P.
  TITLE     Escherichia coli D-malate dehydrogenase, a generalist enzyme active
            in the leucine biosynthesis pathway
  JOURNAL   J. Biol. Chem. 289 (42), 29086-29096 (2014)
   PUBMED   25160617
REFERENCE   2  (residues 1 to 361)
  AUTHORS   Lukas,H., Reimann,J., Kim,O.B., Grimpo,J. and Unden,G.
  TITLE     Regulation of aerobic and anaerobic D-malate metabolism of
            Escherichia coli by the LysR-type regulator DmlR (YeaT)
  JOURNAL   J. Bacteriol. 192 (10), 2503-2511 (2010)
   PUBMED   20233924
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007796
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..361
                     /gene="dmlA"
     Protein         1..361
                     /product="multifunctional
                     D-malate/3-isopropylmalate/tartarate dehydrogenase"
                     /EC_number="1.1.1.83"
                     /EC_number="1.1.1.85"
                     /EC_number="1.1.1.93"
                     /calculated_mol_wt=40157
     Region          2..359
                     /region_name="Iso_dh"
                     /note="Isocitrate/isopropylmalate dehydrogenase; cl00445"
                     /db_xref="CDD:444908"
ORIGIN      
        1 mmktmriaai pgdgigkevl pegirvlqaa aerwgfalsf eqmewascey yshhgkmmpd
       61 dwheqlsrfd aiyfgavgwp dtvpdhislw gsllkfrref dqyvnlrpvr lfpgvpcpla
      121 gkqpgdidfy vvrentegey sslggrvneg tehevviqes vftrrgvdri lryafelaqs
      181 rprktltsat ksnglaismp ywderveama enypeirwdk qhidilcarf vmqperfdvv
      241 vasnlfgdil sdlgpactgt igiapsanln pertfpslfe pvhgsapdiy gknianpiat
      301 iwagammldf lgngderfqq ahngilaaie eviahgpktp dmkgsattpq vadaickiil
      361 r