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MULTISPECIES: choloylglycine hydrolase family protein [Salmonella].


LOCUS       WP_000976498             363 aa            linear   BCT 17-JUL-2024
ACCESSION   WP_000976498
VERSION     WP_000976498.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10087987
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..363
                     /product="choloylglycine hydrolase family protein"
                     /calculated_mol_wt=40151
     Region          25..345
                     /region_name="Ntn_PVA"
                     /note="Penicillin V acylase (PVA), also known as
                     conjugated bile salt acid hydrolase (CBAH), catalyzes the
                     hydrolysis of penicillin V to yield 6-amino penicillanic
                     acid (6-APA), an important key intermediate of
                     semisynthetic penicillins. PVA has an N-terminal...;
                     cd00542"
                     /db_xref="CDD:238303"
     Site            order(25,41,43,49,90,97,162,167,172)
                     /site_type="active"
                     /db_xref="CDD:238303"
ORIGIN      
        1 mmkkskamlf iapalfsyal aaqacttlai qdkqgdifhg rtleymqdlp swltyypagt
       61 qfdkktpdgs qgisyqakyp ilaitstitd gdsrdilegm nsaglsfsen mimnaqlppl
      121 paseykqaip vtslgewala rfatvgevkq aikegkfwsp elhrfgdlks pfhyafydkk
      181 ggsivveven gkfhvydnpt rvmtngpafp whltnlnnyt qltnvdrssg tlggikvmqp
      241 dsgiaiadlp ssdtsvsrfi rgvyyttyap qatsahdamn tlahimsrfd rpknitvdym
      301 gsegegnatr kpvseytvwt tlsdlmhgem mvrgyndiny ktwslsqfkn atapvfekin
      361 vkg