MULTISPECIES: bifunctional adenosylcobinamide

LOCUS       WP_000973176             181 aa            linear   BCT 16-DEC-2020
            kinase/adenosylcobinamide-phosphate guanylyltransferase
            [Enterobacteriaceae].
ACCESSION   WP_000973176
VERSION     WP_000973176.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF004469.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05800
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..181
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..181
                     /gene="cobU"
     Protein         1..181
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0043752 - adenosylcobinamide kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=20033
     Region          1..181
                     /region_name="cobU"
                     /note="adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase;
                     Validated; PRK05800"
                     /db_xref="CDD:235612"
     Site            order(8..10,12,136..139,141,152,156..157,159..160,163,174,
                     176)
                     /site_type="other"
                     /note="trimer interface [polypeptide binding]"
                     /db_xref="CDD:410861"
     Site            order(8..14,29,31..33,35,48,51,57,81..82,85)
                     /site_type="other"
                     /note="GTP binding site [chemical binding]"
                     /db_xref="CDD:410861"
     Site            47
                     /site_type="active"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:410861"
ORIGIN      
        1 mmilvtggar sgksrhaeal igdssqvlyi atsqilddem aariehhrqg rpehwrtver
       61 wqhldeliha dinpnevvll ecvttmvtnl lfdyggdkdp dewdyqameq ainaeiqsli
      121 aacqrcpakv vlvtnevgmg ivpesrlarh frdiagrvnq qlaaaanevw lvvsgigvki
      181 k