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GDP-mannose mannosyl hydrolase [Escherichia coli].


LOCUS       WP_000971417             160 aa            linear   BCT 24-FEB-2020
ACCESSION   WP_000971417
VERSION     WP_000971417.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 160)
  AUTHORS   Gabelli,S.B., Azurmendi,H.F., Bianchet,M.A., Amzel,L.M. and
            Mildvan,A.S.
  TITLE     X-ray, NMR, and mutational studies of the catalytic cycle of the
            GDP-mannose mannosyl hydrolase reaction
  JOURNAL   Biochemistry 45 (38), 11290-11303 (2006)
   PUBMED   16981689
REFERENCE   2  (residues 1 to 160)
  AUTHORS   Xia,Z., Azurmendi,H.F., Lairson,L.L., Withers,S.G., Gabelli,S.B.,
            Bianchet,M.A., Amzel,L.M. and Mildvan,A.S.
  TITLE     Mutational, structural, and kinetic evidence for a dissociative
            mechanism in the GDP-mannose mannosyl hydrolase reaction
  JOURNAL   Biochemistry 44 (25), 8989-8997 (2005)
   PUBMED   15966723
REFERENCE   3  (residues 1 to 160)
  AUTHORS   Gabelli,S.B., Bianchet,M.A., Azurmendi,H.F., Xia,Z., Sarawat,V.,
            Mildvan,A.S. and Amzel,L.M.
  TITLE     Structure and mechanism of GDP-mannose glycosyl hydrolase, a Nudix
            enzyme that cleaves at carbon instead of phosphorus
  JOURNAL   Structure 12 (6), 927-935 (2004)
   PUBMED   15274914
REFERENCE   4  (residues 1 to 160)
  AUTHORS   Legler,P.M., Massiah,M.A. and Mildvan,A.S.
  TITLE     Mutational, kinetic, and NMR studies of the mechanism of E. coli
            GDP-mannose mannosyl hydrolase, an unusual Nudix enzyme
  JOURNAL   Biochemistry 41 (35), 10834-10848 (2002)
   PUBMED   12196023
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011224
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..160
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..160
                     /gene="gmm"
                     /gene_synonym="nudD; wcaH; yefC"
     Protein         1..160
                     /product="GDP-mannose mannosyl hydrolase"
                     /EC_number="3.6.1.-"
                     /calculated_mol_wt=18238
     Region          2..160
                     /region_name="PRK15434"
                     /note="GDP-mannose mannosyl hydrolase"
                     /db_xref="CDD:237966"
ORIGIN      
        1 mmflrqedfa tvvrstplvs ldfivensrg efllgkrtnr paqgywfvpg grvqkdetle
       61 aaferltmae lglrlpitag qfygvwqhfy ddnfsgtdft thyvvlgfrf rvaeeelllp
      121 deqhddyrwl tpdallasnd vhansrayfl aekragvpgl