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winged helix-turn-helix domain-containing protein [Salmonella


LOCUS       WP_000968561             254 aa            linear   BCT 20-JAN-2025
            enterica].
ACCESSION   WP_000968561
VERSION     WP_000968561.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 254)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 254)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
REFERENCE   3  (residues 1 to 254)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007860
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     Protein         1..254
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=29267
     Region          21..117
                     /region_name="CadC1"
                     /note="DNA-binding winged helix-turn-helix (wHTH) domain
                     [Transcription]; COG3710"
                     /db_xref="CDD:442924"
ORIGIN      
        1 mmdavtfriv mnetiflldk rvvfdstkmt lshgneiiri seaethllla fwhglykked
       61 iihfvwenrg gcvsessyyk linqmrndfs siglqssdiv trprvgvsls vaiepikkit
      121 slkvsdenvk gtttrenify knkrhsvfvv ltgaillall ygvftiykap vrnspdsfft
      181 ylgeyndyai yktkedkvtl sevvfafnsl kikiyrqngr hlyyirepnm niflqclnpv
      241 emavpkcitv kery