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LOCUS WP_000964079 189 aa linear BCT 31-DEC-2024 ACCESSION WP_000964079 VERSION WP_000964079.1 KEYWORDS RefSeq. SOURCE Enterobacteriaceae ORGANISM Enterobacteriaceae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales. REFERENCE 1 (residues 1 to 189) AUTHORS Stark,W.M. TITLE The Serine Recombinases JOURNAL Microbiol Spectr 2 (6) (2014) PUBMED 26104451 REFERENCE 2 (residues 1 to 189) AUTHORS Keenholtz,R.A., Rowland,S.J., Boocock,M.R., Stark,W.M. and Rice,P.A. TITLE Structural basis for catalytic activation of a serine recombinase JOURNAL Structure 19 (6), 799-809 (2011) PUBMED 21645851 REFERENCE 3 (residues 1 to 189) AUTHORS Rice,P.A. TITLE Resolving integral questions in site-specific recombination JOURNAL Nat Struct Mol Biol 12 (8), 641-643 (2005) PUBMED 16077726 REFERENCE 4 (residues 1 to 189) AUTHORS Smith,M.C. and Thorpe,H.M. TITLE Diversity in the serine recombinases JOURNAL Mol Microbiol 44 (2), 299-307 (2002) PUBMED 11972771 REFERENCE 5 (residues 1 to 189) AUTHORS Hallet,B. and Sherratt,D.J. TITLE Transposition and site-specific recombination: adapting DNA cut-and-paste mechanisms to a variety of genetic rearrangements JOURNAL FEMS Microbiol Rev 21 (2), 157-178 (1997) PUBMED 9348666 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10132968 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..189 /organism="Enterobacteriaceae" /db_xref="taxon:543" Protein 1..189 /product="recombinase family protein" /GO_function="GO:0000150 - DNA strand exchange activity [Evidence IEA]" /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_process="GO:0006310 - DNA recombination [Evidence IEA]" /GO_process="GO:0015074 - DNA integration [Evidence IEA]" /calculated_mol_wt=20503 Region 3..132 /region_name="SR_ResInv" /note="Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; cd03768" /db_xref="CDD:239737" Site order(8,10,69..70,73) /site_type="active" /note="catalytic residues [active]" /db_xref="CDD:239737" Site 10 /site_type="active" /note="catalytic nucleophile [active]" /db_xref="CDD:239737" Site order(68,113..114,116..117,121) /site_type="other" /note="Presynaptic Site I dimer interface [polypeptide binding]" /db_xref="CDD:239737" Site order(74,79..80,109,112..113,116..117,120,123) /site_type="other" /note="Synaptic Antiparallel dimer interface [polypeptide binding]" /db_xref="CDD:239737" Site order(97..98,100,109..110,113..114,117,121,124,128) /site_type="other" /note="Synaptic Flat tetramer interface [polypeptide binding]" /db_xref="CDD:239737" Site order(97,114,117,121,124,128) /site_type="other" /note="Synaptic Site I dimer interface [polypeptide binding]" /db_xref="CDD:239737" Site order(122,128..129) /site_type="DNA binding" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:239737" Region 144..181 /region_name="HTH_Hin_like" /note="Helix-turn-helix domain of Hin and related proteins; cd00569" /db_xref="CDD:259851" ORIGIN 1 maifgygrvs tsqqdtenqr meleqagwtf dfwfsdvvsg kvpavqrkaf femlskirdg 61 etlvvakldr lgrdaidvlq tvrtladrni kvivhqlgtt dltsaagkll lsmlaavaem 121 erdlliertn agllrakaeg rklgrpakia peargaildk raagvsvsal areygvsrat 181 laallnkgy