MULTISPECIES: bifunctional phosphoribosyl-AMP

LOCUS       WP_000954863             203 aa            linear   BCT 17-NOV-2023
            cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE [Shigella].
ACCESSION   WP_000954863
VERSION     WP_000954863.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 203)
  AUTHORS   Carlomagno,M.S., Chiariotti,L., Alifano,P., Nappo,A.G. and
            Bruni,C.B.
  TITLE     Structure and function of the Salmonella typhimurium and
            Escherichia coli K-12 histidine operons
  JOURNAL   J Mol Biol 203 (3), 585-606 (1988)
   PUBMED   3062174
REFERENCE   2  (residues 1 to 203)
  AUTHORS   Bruni,C.B., Carlomagno,M.S., Formisano,S. and Paolella,G.
  TITLE     Primary and secondary structural homologies between the HIS4 gene
            product of Saccharomyces cerevisiae and the hisIE and hisD gene
            products of Escherichia coli and Salmonella typhimurium
  JOURNAL   Mol Gen Genet 203 (3), 389-396 (1986)
   PUBMED   3528746
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002747.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK02759
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..203
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..203
                     /gene="hisIE"
     Protein         1..203
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /GO_function="GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA]"
                     /GO_function="GO:0004636 - phosphoribosyl-ATP
                     diphosphatase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=22751
     Region          3..202
                     /region_name="PRK02759"
                     /note="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /db_xref="CDD:235067"
ORIGIN      
        1 mlteqqrrel dwektdglmp vivqhavsge vlmlgymnpe aldktiesgk vtffsrtkqr
       61 lwikgetsgn flnvvsiapd cdndtllvla npigptchkg tsscfgntah qwlflyqleq
      121 llaerkyadp etsytaklya sgtkriaqkv geegvetala atvhdrfelt neasdlmyhl
      181 lvllqdqdld lttvienlhk rhq