DEAD/DEAH box helicase [Escherichia coli].

LOCUS       WP_000937974            2113 aa            linear   BCT 26-FEB-2025
ACCESSION   WP_000937974
VERSION     WP_000937974.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 2113)
  AUTHORS   de la Cruz,J., Kressler,D. and Linder,P.
  TITLE     Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and
            related families
  JOURNAL   Trends Biochem Sci 24 (5), 192-198 (1999)
   PUBMED   10322435
REFERENCE   2  (residues 1 to 2113)
  AUTHORS   Aubourg,S., Kreis,M. and Lecharny,A.
  TITLE     The DEAD box RNA helicase family in Arabidopsis thaliana
  JOURNAL   Nucleic Acids Res 27 (2), 628-636 (1999)
   PUBMED   9862990
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012492.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00270.35
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2113
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..2113
                     /product="DEAD/DEAH box helicase"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /calculated_mol_wt=238103
     Region          81..288
                     /region_name="DEXHc_Hrq1-like"
                     /note="DEAH-box helicase domain of Hrq1 and similar
                     proteins; cd17923"
                     /db_xref="CDD:350681"
     Site            order(105..112,148,234..235)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:350681"
     Region          <998..>1126
                     /region_name="YprA"
                     /note="ATP-dependent helicase YprA, contains C-terminal
                     metal-binding DUF1998 domain [Replication, recombination
                     and repair]; COG1205"
                     /db_xref="CDD:440818"
     Region          1548..1638
                     /region_name="MZB"
                     /note="MrfA Zn-binding domain; pfam09369"
                     /db_xref="CDD:462776"
ORIGIN      
        1 mlpsvvsrqv adsvaaflra afplnsplfn genndnvsml eqflaqpetl lkgpylsaql
       61 pfrksdlpln ffpnltlpfp phahqarafq rlgsdapqpt lvatgtgsgk tecfmfplln
      121 hcagasqagv kaiiiypmna latdqasrfa ktiasdpqlh gkvtvglfvg dseiepskkm
      181 saekvitckh tlresppdil ltnykmldyl lmrpgdqplw rynqpgslry lvvdelhtfd
      241 gaqgsdlacl vrrlkhhigv dnqrfacvgt satvgdelgq lldyaktifd qpftddavir
      301 edrytaaeyl qnyaiaysqy pgpevasald pqsyatpvay lngqiplwfp dsdlqlpddl
      361 esddgrekri algsllrrhs vmhvllhdlq ggilserecl enlqvmlaes adharrvlqs
      421 ilaliaqarl evpetehdrq krlqakkarp vlpfvqlrsq lwlremrrlv asvaktprlv
      481 faddvavedr ehylpvihcr dchatgwasl rhgqsvqlet dldgiyrqff ekgrsivlaf
      541 pdnnekavsg ahqklcptcl klnrqssvqc ghcghtellq vlipdmlker kdelefanec
      601 pycnskqgis ilgsraasls avmihqlygs qfnehkklit fsdsvqdaah rasfftartw
      661 plmirgqias vlseketlpl dafaarvcqq trerspddah faanviapnm qwlndyqtlk
      721 negklaensd lpelvslrld wevyseftlr arigrtleat gyavagvdkd rfnpaitalh
      781 qqlceelgde msgvsveqva hlalgviwyq rqagavmhpa fesyrrdgtt fmmtqkerts
      841 rympsigpkt rkpayasfek ingfhrliga ksnpswyqhw inrtlsngnn lfissvaetv
      901 lrrlftalki agvvkdfdtk greawglvps alvvsrdvvq lncsccrevv rapadqgwqw
      961 rnapclslrc egryqevdnt atwrwenmdi arvqgaehtg llsredrevt eksfyrgnqp
     1021 wninllsatp tlemgidvgd lstvllcsvp paqanylqri gragrkdgna lnitvaegnp
     1081 hdqfffeepl emmqgqvqap gvflnatail erqlaafcmd nwvktgvpes aicknvkqml
     1141 delefgrksg fpynllryie qhhaeiaaqf taifpdlaae trqqllsylq gapgqrslvq
     1201 rieealkllv edrkslrsri dklkrsidkl enaprdqnfd sdmreltser qalmalvnqi
     1261 nnkqtlnflt degllpnyaf peagitlrsv lwrrkeggea reyqnttfey erpastalae
     1321 laplnnfyag ghkveieqid lkvsepenwr icshcnysen idqtgdqhky cpkcgtpgwa
     1381 dagqkttllk lrqvyarasa rdsqisdesd srepaffqrq llvsfekedv saayaieege
     1441 vpfgfeflsk vtlrdinfgk maddanelmi ageakkrtgf kvclgcgmvq rprdheprhd
     1501 lsckyrtepe kakfedylyl yrqlesealr illpvssysn drvveaslga aiqlglkhyf
     1561 kgnvdhlkgv vyrepenege swrqylviyd tvpggtgslk elmrtpdnll kllelayqai
     1621 vecscnndth kdgcyrcvya yrdrgrmkyv srdqarllla kilqardsir vidsiknisl
     1681 eammgselek rfisclqenk nlivsrsyah qgagwiintr sepmmswhlk aqvdlgakea
     1741 vgipcrpdyv lyplmqsdai kpvaifldgf afhknsvaed vqkrqairds gnfwvwtvtw
     1801 adlkepglkh vqdvlglghn pdmkqpkfyn lfhdtnfaal easfrernsf allldyladp
     1861 ggrtqlwqrm aaahawvwld vkksqdagtk qkyayemqen apawrlaell pdepfvfggl
     1921 ldscnssqqf ielasvlpqq aikpttsvaq mrswlrlhic fddrytqddg yeaglngfwr
     1981 lvnllqflpd mtftsrkavh lpqesvdtkv satpeavpet deswaeiief gllsaeeial
     2041 lqshslsapt lgyelqndeg eiiaeadlaw psqkwaliid nqefiplftt rgwhvafgpi
     2101 dentlqhlsg gdk