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exodeoxyribonuclease VII large subunit [Escherichia coli].


LOCUS       WP_000937887             456 aa            linear   BCT 08-JUN-2021
ACCESSION   WP_000937887
VERSION     WP_000937887.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 456)
  AUTHORS   Poleszak,K., Kaminska,K.H., Dunin-Horkawicz,S., Lupas,A.,
            Skowronek,K.J. and Bujnicki,J.M.
  TITLE     Delineation of structural domains and identification of
            functionally important residues in DNA repair enzyme exonuclease
            VII
  JOURNAL   Nucleic Acids Res 40 (16), 8163-8174 (2012)
   PUBMED   22718974
REFERENCE   2  (residues 1 to 456)
  AUTHORS   Vales,L.D., Rabin,B.A. and Chase,J.W.
  TITLE     Subunit structure of Escherichia coli exonuclease VII
  JOURNAL   J Biol Chem 257 (15), 8799-8805 (1982)
   PUBMED   6284744
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00237.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..456
                     /gene="xseA"
     Protein         1..456
                     /product="exodeoxyribonuclease VII large subunit"
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=51603
     Region          5..447
                     /region_name="XseA"
                     /note="Exonuclease VII, large subunit [Replication,
                     recombination and repair]; COG1570"
                     /db_xref="CDD:441178"
ORIGIN      
        1 mlpsqspaif tvsrlnqtvr lllehemgqv wisgeisnft qpasghwyft lkddtaqvrc
       61 amfrnsnrrv tfrpqhgqqv lvranitlye prgdyqiive smqpagegll qqkyeqlkak
      121 lqaeglfdlq ykkplpspah cvgvitsktg aalhdilhvl krrdpslpvi iyptavqgdd
      181 apgqivraie lanqcnecdv livgrgggsl edlwsfnder varaifasri pvvsavghet
      241 dvtiadfvad lraptpsaaa evvsrnqqel lrqvqstrqr lemamdyyla nrtrrftqih
      301 hrlqqqhpql rlarqqtmle rlqkrmsfal enqlkragqq qqrltqrlnq qnpqpkihra
      361 qtriqqleyr laetlraqls atrerfgnav thleavspls tlargysvtt atdgkvlkkv
      421 kqvkagemlt trledgwves evkniqpvkk srkkvh