MULTISPECIES: site-specific integrase [Shigella].

LOCUS       WP_000920423             536 aa            linear   BCT 17-NOV-2023
ACCESSION   WP_000920423
VERSION     WP_000920423.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 536)
  AUTHORS   Grainge,I. and Jayaram,M.
  TITLE     The integrase family of recombinase: organization and function of
            the active site
  JOURNAL   Mol Microbiol 33 (3), 449-456 (1999)
   PUBMED   10577069
REFERENCE   2  (residues 1 to 536)
  AUTHORS   Gopaul,D.N. and Duyne,G.D.
  TITLE     Structure and mechanism in site-specific recombination
  JOURNAL   Curr Opin Struct Biol 9 (1), 14-20 (1999)
   PUBMED   10047575
REFERENCE   3  (residues 1 to 536)
  AUTHORS   Esposito,D. and Scocca,J.J.
  TITLE     The integrase family of tyrosine recombinases: evolution of a
            conserved active site domain
  JOURNAL   Nucleic Acids Res 25 (18), 3605-3614 (1997)
   PUBMED   9278480
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10100329
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Shigella"
                     /db_xref="taxon:620"
     Protein         1..536
                     /product="site-specific integrase"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=60366
     Region          7..65
                     /region_name="DUF6538"
                     /note="Domain of unknown function (DUF6538); pfam20172"
                     /db_xref="CDD:466323"
     Region          324..513
                     /region_name="INT_C_like_1"
                     /note="Uncharacterized site-specific tyrosine recombinase,
                     C-terminal catalytic domain; cd01184"
                     /db_xref="CDD:271184"
     Site            order(362,475,478..479,511)
                     /site_type="active"
                     /db_xref="CDD:271184"
ORIGIN      
        1 mlksrtylyq rngvfyirlr mkttsrltas lpshnrykla svslrtkdrr tamahsrhik
       61 salkaihadn pnasyeelre hlktivewel svsrddlndp esyqlyvdqy ddiksnlrea
      121 vaterltvdq hryindvigv lkacqdrlng dssgllsyle petgslrpsv slsvlaepev
      181 pepkaltlas lieqyeqena qnwkpatlse nrashstlie ifdyldiqdv gkatradmlr
      241 vrevlqqlpk nrkqrfksmp lsdllnresk tdcldvvtin nkylikmaav fkwavrndli
      301 aknlteglel kvpqrkasda rdafspeqvg qllvaakays qktsgkpyhy yvtalaaitg
      361 arlnevaqlq vkdvrtteag tvfihinedd sslpgksikn ahsdrcvplv dgaygfvlad
      421 fmslvedrrk tegdnamvfn glklmkngyg eqvskwfnrt llpkvladrs glafhsfrht
      481 vatqlkqhgv elayaqaimg hssgsitydr yakevevetl keklaeslsv kkidgk