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MULTISPECIES: chorismate synthase [Vibrio].


LOCUS       WP_000918437             361 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_000918437
VERSION     WP_000918437.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 361)
  AUTHORS   Viola,C.M., Saridakis,V. and Christendat,D.
  TITLE     Crystal structure of chorismate synthase from Aquifex aeolicus
            reveals a novel beta alpha beta sandwich topology
  JOURNAL   Proteins 54 (1), 166-169 (2004)
   PUBMED   14705034
REFERENCE   2  (residues 1 to 361)
  AUTHORS   Ahn,H.J., Yang,J.K., Lee,B.I., Yoon,H.J., Kim,H.W. and Suh,S.W.
  TITLE     Crystallization and preliminary X-ray crystallographic studies of
            chorismate synthase from Helicobacter pylori
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 59 (Pt 3), 569-571 (2003)
   PUBMED   12595729
REFERENCE   3  (residues 1 to 361)
  AUTHORS   Fitzpatrick,T.B., Killer,P., Thomas,R.M., Jelesarov,I., Amrhein,N.
            and Macheroux,P.
  TITLE     Chorismate synthase from the hyperthermophile Thermotoga maritima
            combines thermostability and increased rigidity with catalytic and
            spectral properties similar to mesophilic counterparts
  JOURNAL   J. Biol. Chem. 276 (21), 18052-18059 (2001)
   PUBMED   11279147
REFERENCE   4  (residues 1 to 361)
  AUTHORS   Horsburgh,M.J., Foster,T.J., Barth,P.T. and Coggins,J.R.
  TITLE     Chorismate synthase from Staphylococcus aureus
  JOURNAL   Microbiology (Reading, Engl.) 142 (Pt 10), 2943-2950 (1996)
   PUBMED   8885411
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003793.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05382
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     gene            1..361
                     /gene="aroC"
     Protein         1..361
                     /product="chorismate synthase"
                     /EC_number="4.2.3.5"
                     /GO_function="GO:0004107 - chorismate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=38974
     Region          8..361
                     /region_name="PRK05382"
                     /note="chorismate synthase; Validated"
                     /db_xref="CDD:235438"
     Site            order(11..17,24,26,28,32..33,66..67,69..70,77..78,80,82,
                     84,111..115,125..126,134,196,201..206,217,219..221,225,
                     227..228,231..233,235..236,238,241..245,248..249,251..252,
                     256..257,273,276..278,280..282,289,291..294,297,335)
                     /site_type="other"
                     /note="Tetramer interface [polypeptide binding]"
                     /db_xref="CDD:143612"
     Site            order(19,48,105..106,126..129,132,238..239,292..293,
                     295..297,324,328)
                     /site_type="active"
                     /db_xref="CDD:143612"
     Site            order(105..107,125,127,237..239,293,295..297,321,324,327)
                     /site_type="other"
                     /note="FMN-binding site [chemical binding]"
                     /db_xref="CDD:143612"
ORIGIN      
        1 magnsigqhf rvttfgeshg ialgcivdgc ppgltisead lqvdldrrrp gtsryttqrr
       61 epdevkilsg vfegkttgts igllientdq rskdysdikd kfrpghadyt yhqkygvrdy
      121 rgggrssare tamrvaagai akkylqqefg ievraylsqm gevaidkvdw neienndffc
      181 pdvdkvaafd elirelkkeg dsigakiqvv atgvpvglge pvfdrldadi ahalmsinav
      241 kgveigdgfd vvrqkgsqhr dpltpqgfrs nhsggilggi ssgqdivani alkptssitv
      301 pgetidvnge ptelitkgrh dpcvgiravp iaeamlaivl mdhllrhrgq nqgvvtttpk
      361 i