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LOCUS WP_000918155 844 aa linear BCT 01-JUL-2024 [Enterobacteriaceae]. ACCESSION WP_000918155 VERSION WP_000918155.1 KEYWORDS RefSeq. SOURCE Enterobacteriaceae ORGANISM Enterobacteriaceae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales. REFERENCE 1 (residues 1 to 844) AUTHORS Charpentier,X., Chalut,C., Remy,M.H. and Masson,J.M. TITLE Penicillin-binding proteins 1a and 1b form independent dimers in Escherichia coli JOURNAL J Bacteriol 184 (13), 3749-3752 (2002) PUBMED 12057973 REFERENCE 2 (residues 1 to 844) AUTHORS Chalut,C., Remy,M.H. and Masson,J.M. TITLE Disulfide bridges are not involved in penicillin-binding protein 1b dimerization in Escherichia coli JOURNAL J Bacteriol 181 (9), 2970-2972 (1999) PUBMED 10217796 REFERENCE 3 (residues 1 to 844) AUTHORS Vollmer,W., von Rechenberg,M. and Holtje,J.V. TITLE Demonstration of molecular interactions between the murein polymerase PBP1B, the lytic transglycosylase MltA, and the scaffolding protein MipA of Escherichia coli JOURNAL J Biol Chem 274 (10), 6726-6734 (1999) PUBMED 10037771 REFERENCE 4 (residues 1 to 844) AUTHORS Zijderveld,C.A., Aarsman,M.E., den Blaauwen,T. and Nanninga,N. TITLE Penicillin-binding protein 1B of Escherichia coli exists in dimeric forms JOURNAL J Bacteriol 173 (18), 5740-5746 (1991) PUBMED 1885547 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF007061.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK09506 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..844 /organism="Enterobacteriaceae" /db_xref="taxon:543" gene 1..844 /gene="mrcB" Protein 1..844 /product="bifunctional glycosyl transferase/transpeptidase" /EC_number="2.4.99.28" /GO_component="GO:0009274 - peptidoglycan-based cell wall [Evidence IEA]" /GO_function="GO:0008658 - penicillin binding [Evidence IEA]" /GO_function="GO:0008955 - peptidoglycan glycosyltransferase activity [Evidence IEA]" /GO_process="GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]" /GO_process="GO:0046677 - response to antibiotic [Evidence IEA]" /calculated_mol_wt=94134 Region 1..843 /region_name="mrcB" /note="bifunctional glycosyl transferase/transpeptidase; Reviewed; PRK09506" /db_xref="CDD:236544" ORIGIN 1 magndrepig rkgkptrpvk qkvsrrryed dddyddyddy edeepmprkg kgkgkgrkpr 61 gkrgwlwlll klaivfavli aiygvyldqk irsridgkvw qlpaavygrm vnlepdmtis 121 knemvkllea tqyrqvskmt rpgeftvqan siemirrpfd fpdskegqvr arltfdgdhl 181 ativnmennr qfgffrldpr litmisspng eqrlfvprsg fpdllvdtll atedrhfyeh 241 dgislysigr avlanltagr tvqgastltq qlvknlflss ersywrkane aymalimdar 301 yskdrilely mnevylgqsg dneirgfpla slyyfgrpve elsldqqall vgmvkgasiy 361 npwrnpklal errnlvlrll qqqqiidqel ydmlsarplg vqprggvisp qpafmqlvrq 421 elqaklgdkv kdlsgvkift tfdsvaqdaa ekaavegipa lkkqrklsdl etaivvvdrf 481 sgevramvgg sepqfagynr amqarrsigs lakpatylta lsqpkiyrln twiadapial 541 rqpngqvwsp qnddrryses grvmlvdalt rsmnvptvnl gmalglpavt dtwiklgvpk 601 dqlhpvpaml lgalnltpie vaqafqtias ggnraplsal rsviaedgkv lyqsfpqaer 661 avpaqaaylt lwtmqqvvqr gtgrqlgaky pnlhlagktg ttnnnvdtwf agidgstvti 721 twvgrdnnqp tklygasgam siyqrylanq tptplnlvpp ediadmgvdy dgnfvcsggm 781 rvlpvwtsdp qslcqqsemq qqpsgnpfdq ssqpqqqpqq qpaqqeqkds dgvagwikdm 841 fgsn