MULTISPECIES: SPI-1 type III secretion system needle tip complex

LOCUS       WP_000909019             409 aa            linear   BCT 10-JUL-2019
            protein SipC [Salmonella].
ACCESSION   WP_000909019
VERSION     WP_000909019.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 409)
  AUTHORS   Kroger,C., Dillon,S.C., Cameron,A.D., Papenfort,K.,
            Sivasankaran,S.K., Hokamp,K., Chao,Y., Sittka,A., Hebrard,M.,
            Handler,K., Colgan,A., Leekitcharoenphon,P., Langridge,G.C.,
            Lohan,A.J., Loftus,B., Lucchini,S., Ussery,D.W., Dorman,C.J.,
            Thomson,N.R., Vogel,J. and Hinton,J.C.
  TITLE     The transcriptional landscape and small RNAs of Salmonella enterica
            serovar Typhimurium
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 109 (20), E1277-E1286 (2012)
   PUBMED   22538806
REFERENCE   2  (residues 1 to 409)
  AUTHORS   McGhie,E.J., Hayward,R.D. and Koronakis,V.
  TITLE     Cooperation between actin-binding proteins of invasive Salmonella:
            SipA potentiates SipC nucleation and bundling of actin
  JOURNAL   EMBO J. 20 (9), 2131-2139 (2001)
   PUBMED   11331579
REFERENCE   3  (residues 1 to 409)
  AUTHORS   Zhao,L., Ezak,T., Li,Z.Y., Kawamura,Y., Hirose,K. and Watanabe,H.
  TITLE     Vi-Suppressed wild strain Salmonella typhi cultured in high
            osmolarity is hyperinvasive toward epithelial cells and destructive
            of Peyer's patches
  JOURNAL   Microbiol. Immunol. 45 (2), 149-158 (2001)
   PUBMED   11293481
REFERENCE   4  (residues 1 to 409)
  AUTHORS   Scherer,C.A., Cooper,E. and Miller,S.I.
  TITLE     The Salmonella type III secretion translocon protein SspC is
            inserted into the epithelial cell plasma membrane upon infection
  JOURNAL   Mol. Microbiol. 37 (5), 1133-1145 (2000)
   PUBMED   10972831
REFERENCE   5  (residues 1 to 409)
  AUTHORS   Hayward,R.D. and Koronakis,V.
  TITLE     Direct nucleation and bundling of actin by the SipC protein of
            invasive Salmonella
  JOURNAL   EMBO J. 18 (18), 4926-4934 (1999)
   PUBMED   10487745
REFERENCE   6  (residues 1 to 409)
  AUTHORS   Hueck,C.J., Hantman,M.J., Bajaj,V., Johnston,C., Lee,C.A. and
            Miller,S.I.
  TITLE     Salmonella typhimurium secreted invasion determinants are
            homologous to Shigella Ipa proteins
  JOURNAL   Mol. Microbiol. 18 (3), 479-490 (1995)
   PUBMED   8748032
REFERENCE   7  (residues 1 to 409)
  AUTHORS   Hermant,D., Menard,R., Arricau,N., Parsot,C. and Popoff,M.Y.
  TITLE     Functional conservation of the Salmonella and Shigella effectors of
            entry into epithelial cells
  JOURNAL   Mol. Microbiol. 17 (4), 781-789 (1995)
   PUBMED   8801431
REFERENCE   8  (residues 1 to 409)
  AUTHORS   Kaniga,K., Tucker,S., Trollinger,D. and Galan,J.E.
  TITLE     Homologs of the Shigella IpaB and IpaC invasins are required for
            Salmonella typhimurium entry into cultured epithelial cells
  JOURNAL   J. Bacteriol. 177 (14), 3965-3971 (1995)
   PUBMED   7608068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000658
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..409
                     /gene="sipC"
     Protein         1..409
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipC"
                     /calculated_mol_wt=42852
     Region          1..409
                     /region_name="PRK15373"
                     /note="IpaC/SipC family type III secretion system needle
                     tip complex protein"
                     /db_xref="CDD:185271"
ORIGIN      
        1 mlisnvginp aaylnnhsve nssqtasqsv sakdilnsig issskvsdlg lsptlsapap
       61 gvltqtpgti tsflkasiqn tdmnqdlnal annvttkane vvqtqlreqq aevgkffdis
      121 gmsssavall aaantlmltl nqadsklsgk lslvsfdaak ttassmmreg mnalsgsisq
      181 salqlgitgv gakleykglq nergalkhna akidklttes hsiknvlngq nsvklgaegv
      241 dslkslnmkk tgtdatknln datlksnagt sateslgikd snkqispehq ailskrlesv
      301 esdirleqnt mdmtridark mqmtgdlimk nsvtvggiag asgqyaatqe rseqqisqvn
      361 nrvastasde aressrksts liqemlktme sinqskasal aaiagnira