Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: preprotein translocase subunit SecA


LOCUS       WP_000905780             901 aa            linear   BCT 30-DEC-2022
            [Enterobacteriaceae].
ACCESSION   WP_000905780
VERSION     WP_000905780.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 901)
  AUTHORS   Karamyshev,A.L. and Johnson,A.E.
  TITLE     Selective SecA association with signal sequences in ribosome-bound
            nascent chains: a potential role for SecA in ribosome targeting to
            the bacterial membrane
  JOURNAL   J Biol Chem 280 (45), 37930-37940 (2005)
   PUBMED   16120599
REFERENCE   2  (residues 1 to 901)
  AUTHORS   Matousek,W.M. and Alexandrescu,A.T.
  TITLE     NMR structure of the C-terminal domain of SecA in the free state
  JOURNAL   Biochim Biophys Acta 1702 (2), 163-171 (2004)
   PUBMED   15488768
REFERENCE   3  (residues 1 to 901)
  AUTHORS   Papanikou,E., Karamanou,S., Baud,C., Sianidis,G., Frank,M. and
            Economou,A.
  TITLE     Helicase Motif III in SecA is essential for coupling preprotein
            binding to translocation ATPase
  JOURNAL   EMBO Rep 5 (8), 807-811 (2004)
   PUBMED   15272299
REFERENCE   4  (residues 1 to 901)
  AUTHORS   Ding,H., Hunt,J.F., Mukerji,I. and Oliver,D.
  TITLE     Bacillus subtilis SecA ATPase exists as an antiparallel dimer in
            solution
  JOURNAL   Biochemistry 42 (29), 8729-8738 (2003)
   PUBMED   12873133
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009538.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK12904
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..901
                     /gene="secA"
     Protein         1..901
                     /product="preprotein translocase subunit SecA"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006605 - protein targeting [Evidence
                     IEA]"
                     /GO_process="GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /GO_process="GO:0017038 - protein import [Evidence IEA]"
                     /calculated_mol_wt=101834
     Region          2..901
                     /region_name="SecA"
                     /note="Preprotein translocase subunit SecA (ATPase, RNA
                     helicase) [Intracellular trafficking, secretion, and
                     vesicular transport]; COG0653"
                     /db_xref="CDD:440418"
ORIGIN      
        1 mliklltkvf gsrndrtlrr mrkvvniina mepemeklsd eelkgktaef rarlekgevl
       61 enlipeafav vreaskrvfg mrhfdvqllg gmvlnercia emrtgegktl tatlpaylna
      121 ltgkgvhvvt vndylaqrda ennrplfefl gltvginlpg mpapakreay aaditygtnn
      181 eygfdylrdn mafspeervq rklhyalvde vdsilidear tpliisgpae dssemykrvn
      241 kiiphlirqe kedsetfqge ghfsvdeksr qvnlterglv lieellvkeg imdegeslys
      301 panimlmhhv taalrahalf trdvdyivkd geviivdeht grtmqgrrws dglhqaveak
      361 egvqiqnenq tlasitfqny frlyeklagm tgtadteafe fssiykldtv vvptnrpmir
      421 kdlpdlvymt eaekiqaiie dikertakgq pvlvgtisie kselvsnelt kagikhnvln
      481 akfhaneaai vaqagypaav tiatnmagrg tdivlggswq aevaalenpt aeqiekikad
      541 wqvrhdavla agglhiigte rhesrridnq lrgrsgrqgd agssrfylsm edalmrifas
      601 drvsgmmrkl gmkpgeaieh pwvtkaiana qrkvesrnfd irkqlleydd vandqrraiy
      661 sqrnelldvs dvsetinsir edvfkatida yippqsleem wdipglqerl kndfdldlpi
      721 aewldkepel heetlreril aqsievyqrk eevvgaemmr hfekgvmlqt ldslwkehla
      781 amdylrqgih lrgyaqkdpk qeykresfsm faamleslky evistlskvq vrmpeeveel
      841 eqqrrmeaer laqmqqlshq dddsaaaaal aaqtgerkvg rndpcpcgsg kkykqchgrl
      901 q