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MULTISPECIES: ion channel protein [Enterobacteriaceae].


LOCUS       WP_000903148             418 aa            linear   BCT 16-DEC-2020
ACCESSION   WP_000903148
VERSION     WP_000903148.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002971.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK03655
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..418
                     /product="ion channel protein"
                     /GO_function="GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA]"
                     /calculated_mol_wt=43443
     Region          1..414
                     /region_name="PRK03655"
                     /note="putative ion channel protein; Provisional"
                     /db_xref="CDD:235148"
     Site            order(85..89,118..122,323..327)
                     /site_type="active"
                     /note="Cl- selectivity filter [active]"
                     /db_xref="CDD:238233"
     Site            order(86,88,120..121,323..325)
                     /site_type="other"
                     /note="Cl- binding residues [ion binding]"
                     /db_xref="CDD:238233"
     Site            120
                     /site_type="active"
                     /note="pore gating glutamate residue [active]"
                     /db_xref="CDD:238233"
     Site            order(164,173,191,198,365,368,376,384,391..392)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238233"
ORIGIN      
        1 mlhprartml llslpavaig iasslilivv mkiasvlqnl lwqrlpgtlg iaqdsplwii
       61 gvltltgiav glvirfsqgh agpdpacepl igapvppsal pglivalilg laggvslgpe
      121 hpimtvnial avaigarllp rvnrmewtil asagtigalf gtpvaaalif sqtlngssev
      181 plwdrlfapl maaaagaltt glffhphfsl piahygqmem tdilsgaiva aiaiaagmva
      241 vwclprlham mhqmknpvlv lgiggfilgi lgviggpvsl fkgldemqqm vanqafstsd
      301 yfllavikla alvvaaasgf rggrifpavf vgvalglmlh ehvpavpaai tvscailgiv
      361 lvvtrdgwls lfmaavvvpn ttllpllciv mlpawlllag kpmmmvnrpk qqpphdnv