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MULTISPECIES: lipopolysaccharide biosynthesis protein [Shigella].


LOCUS       WP_000896846             449 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000896846
VERSION     WP_000896846.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 449)
  AUTHORS   Samuel,G. and Reeves,P.
  TITLE     Biosynthesis of O-antigens: genes and pathways involved in
            nucleotide sugar precursor synthesis and O-antigen assembly
  JOURNAL   Carbohydr Res 338 (23), 2503-2519 (2003)
   PUBMED   14670712
REFERENCE   2  (residues 1 to 449)
  AUTHORS   Liu,D., Cole,R.A. and Reeves,P.R.
  TITLE     An O-antigen processing function for Wzx (RfbX): a promising
            candidate for O-unit flippase
  JOURNAL   J Bacteriol 178 (7), 2102-2107 (1996)
   PUBMED   8606190
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454936
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Shigella"
                     /db_xref="taxon:620"
     Protein         1..449
                     /product="lipopolysaccharide biosynthesis protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /calculated_mol_wt=48548
     Region          15..427
                     /region_name="RfbX"
                     /note="Membrane protein involved in the export of
                     O-antigen and teichoic acid [Cell wall/membrane/envelope
                     biogenesis]; COG2244"
                     /db_xref="CDD:441845"
ORIGIN      
        1 magfnikhwf adgafrtiir nsawlgssnv esallgllal scagkgmtpa mfgvlvivqs
       61 yaksisdfik fqtwqlvvqy gtpaltnnnp qqfrnvvsfs fsldivsgav aivggiallp
      121 flshslgldd qsfwlaalyc tlipsmasst ptgilravdr fdliavqqat kpflraagsv
      181 aawyfdfgfv gfviawyvsn lvggtmywwf aarelrrrni hnafklnlfe sarhikgaws
      241 fvwstniahs iwsarnscst vlvgivlgpa aaglfkiamt ffdaagtpag llgksfypev
      301 mrldprttrp wllgvksgll aggigilval avlivgkpli slvfgvkyle aydliqvmlg
      361 aivismlgfp qeslllmagk qraflvaqti asigyivllf mfchlfgvlg aafayfggqc
      421 ldvalslipt lkaffqrhsl lynaageks