LysR family transcriptional regulator [Escherichia coli].

LOCUS       WP_000890349             323 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000890349
VERSION     WP_000890349.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 323)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 323)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444112
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..323
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=35995
     Region          28..86
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          116..317
                     /region_name="PBP2_CrgA_like_3"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08472"
                     /db_xref="CDD:176161"
     Site            order(126,130,169,183,185,249,266,293)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176161"
     Site            order(127..128,132..133,135..136,139,143,145..151,212,
                     243..247,254..255,258)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176161"
ORIGIN      
        1 mlekiinnai callfrceqq svkemdkiha mqlfikvael esfsraadff alpkgsvsrq
       61 iqalehqlgt qllqrttrrv kltpegmtyy qrakdvlsnl neldglfqqd atsisgklri
      121 dippgiaksl llphlsefly qhpgielels shdrpvdilh dgfdcvirtg alpedgviar
      181 plgkltmvnc asphyltrfg ypqnpddlts haivrytphl gvhplgfeva svngvqwfks
      241 ggmltvnsse nylaaglagl giiqipriav realragrli evlpgyraep lslslvypqr
      301 relsrrvnlf mqwlagvmke yld