MULTISPECIES: bifunctional aconitate hydratase 2/2-methylisocitrate

LOCUS       WP_000888962             865 aa            linear   BCT 04-JUN-2024
            dehydratase [Salmonella].
ACCESSION   WP_000888962
VERSION     WP_000888962.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 865)
  AUTHORS   Bradbury,A.J., Gruer,M.J., Rudd,K.E. and Guest,J.R.
  TITLE     The second aconitase (AcnB) of Escherichia coli
  JOURNAL   Microbiology (Reading) 142 (Pt 2), 389-400 (1996)
   PUBMED   8932712
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00117.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..865
                     /gene="acnB"
     Protein         1..865
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /calculated_mol_wt=93398
     Region          1..864
                     /region_name="AcnB"
                     /note="Aconitase B [Energy production and conversion];
                     COG1049"
                     /db_xref="CDD:440670"
ORIGIN      
        1 mleeyrkhva eraaqgivpk pldatqmaal vellktppvg eeeflldlli nrvppgvdea
       61 ayvkagflaa vakgdttspl vspekaiell gtmqggynih plidalddak lapiaakals
      121 htllmfdnfy dveekakagn eyakqvmqsw adaewflsrp plaekitvtv fkvtgetntd
      181 dlspapdaws rpdiplhaqa mlknaregie pdqpgvvgpi kqiealqkkg yplayvgdvv
      241 gtgssrksat nsvlwfmgdd ipnvpnkrgg glclggkiap iffntmedag alpievdvsn
      301 lnmgdvidvy pykgevrnhe tgellatfel ktdvlidevr aggripliig rglttkarea
      361 lglphsdvfr qakdvaessr gfslaqkmvg racgvkgirp gaycepkmts vgsqdttgpm
      421 trdelkdlac lgfsadlvmq sfchtaaypk pvdvtthhtl pdfimnrggv slrpgdgvih
      481 swlnrmllpd tvgtggdsht rfpigisfpa gsglvafaaa tgvmpldmpe svlvrfkgkm
      541 qpgitlrdlv haiplyaikq glltvekkgk knifsgrile ieglpdlkve qafeltdasa
      601 ersaagctik lnkepiveyl tsnivllkwm iaegygdrrt lerriqgmek wladpqllea
      661 dadaeyaavi didladikep ilcapndpdd arllsdvqge kidevfigsc mtnighfraa
      721 gklldnhkgq lptrlwvapp trmdaaqlte egyysvfgks garieipgcs lcmgnqarva
      781 dgatvvstst rnfpnrlgtg anvflasael aavaaligkl ptpeeyqtyv aqvdktavdt
      841 yrylnfdqls qytekadgvi fqtav