MULTISPECIES: imidazole glycerol phosphate synthase subunit HisF

LOCUS       WP_000880182             258 aa            linear   BCT 14-APR-2021
            [Enterobacteriaceae].
ACCESSION   WP_000880182
VERSION     WP_000880182.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 258)
  AUTHORS   Chaudhuri,B.N., Lange,S.C., Myers,R.S., Davisson,V.J. and
            Smith,J.L.
  TITLE     Toward understanding the mechanism of the complex cyclization
            reaction catalyzed by imidazole glycerolphosphate synthase: crystal
            structures of a ternary complex and the free enzyme
  JOURNAL   Biochemistry 42 (23), 7003-7012 (2003)
   PUBMED   12795595
REFERENCE   2  (residues 1 to 258)
  AUTHORS   Fujimori,K. and Ohta,D.
  TITLE     An Arabidopsis cDNA encoding a bifunctional glutamine
            amidotransferase/cyclase suppresses the histidine auxotrophy of a
            Saccharomyces cerevisiae his7 mutant
  JOURNAL   FEBS Lett 428 (3), 229-234 (1998)
   PUBMED   9654139
REFERENCE   3  (residues 1 to 258)
  AUTHORS   Kuenzler,M., Balmelli,T., Egli,C.M., Paravicini,G. and Braus,G.H.
  TITLE     Cloning, primary structure, and regulation of the HIS7 gene
            encoding a bifunctional glutamine amidotransferase: cyclase from
            Saccharomyces cerevisiae
  JOURNAL   J Bacteriol 175 (17), 5548-5558 (1993)
   PUBMED   8366040
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00735.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..258
                     /gene="hisF"
     Protein         1..258
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=28323
     Region          1..256
                     /region_name="hisF"
                     /note="imidazoleglycerol phosphate synthase, cyclase
                     subunit; TIGR00735"
                     /db_xref="CDD:273241"
     Site            order(19,50,82,103..104,128,130,150,177,182..183,207..209,
                     231..232)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:240082"
     Site            order(40,45,67,71,74,76,95,98..99,123,173,201,226)
                     /site_type="other"
                     /note="glutamase interaction surface [polypeptide
                     binding]"
                     /db_xref="CDD:240082"
ORIGIN      
        1 mlakriipcl dvrdgqvvkg vqfrnheiig divplakrya eegadelvfy ditassdgrv
       61 vdkswvsrva evidipfcva ggiksledaa kilsfgadki sinspaladp tlitrladrf
      121 gvqcivvgid twydaetgky hvnqytgdes rtrvtqwetl dwvqevqkrg ageivlnmmn
      181 qdgvrngydl eqlkkvrevc hvpliasgga gtmehfleaf rdadvdgala asvfhkqiin
      241 igelkaylat qgveiric