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LOCUS WP_000859023 321 aa linear BCT 19-FEB-2025 ACCESSION WP_000859023 VERSION WP_000859023.1 KEYWORDS RefSeq. SOURCE Salmonella ORGANISM Salmonella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae. REFERENCE 1 (residues 1 to 321) AUTHORS Maddocks,S.E. and Oyston,P.C.F. TITLE Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins JOURNAL Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008) PUBMED 19047729 REFERENCE 2 (residues 1 to 321) AUTHORS Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M. TITLE The many faces of the helix-turn-helix domain: transcription regulation and beyond JOURNAL FEMS Microbiol Rev 29 (2), 231-262 (2005) PUBMED 15808743 REFERENCE 3 (residues 1 to 321) AUTHORS Rosinski,J.A. and Atchley,W.R. TITLE Molecular evolution of helix-turn-helix proteins JOURNAL J Mol Evol 49 (3), 301-309 (1999) PUBMED 10473770 REFERENCE 4 (residues 1 to 321) AUTHORS Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W. TITLE The Venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors JOURNAL AAPS PharmSci 1 (2), E2 (1999) PUBMED 11741199 REFERENCE 5 (residues 1 to 321) AUTHORS Schell,M.A. TITLE Molecular biology of the LysR family of transcriptional regulators JOURNAL Annu Rev Microbiol 47, 597-626 (1993) PUBMED 8257110 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10444120 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..321 /organism="Salmonella" /db_xref="taxon:590" Protein 1..321 /product="LysR family transcriptional regulator" /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /calculated_mol_wt=35762 Region 21..79 /region_name="HTH_1" /note="Bacterial regulatory helix-turn-helix protein, lysR family; pfam00126" /db_xref="CDD:459683" Region 108..304 /region_name="PBP2_CrgA_like_9" /note="The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; cd08479" /db_xref="CDD:176168" Site order(118,122,161,175,177,240,257,283) /site_type="active" /note="putative effector binding pocket [active]" /db_xref="CDD:176168" Site order(119..120,124..125,127..128,131,135,137..143,204, 234..238,245..246,249) /site_type="other" /note="putative dimerization interface [polypeptide binding]" /db_xref="CDD:176168" ORIGIN 1 mkttpvgkkh rqplegwpsv edlfvfvtva rnggfaraal elglspsyis kriailekcl 61 narlffrnnr vmrltpegen alggamqvvs emdgfvsrld nqrgvlagni tincsfgfgh 121 kyvaealssf miaypditvk ltltdrevdl veegidieir vgddinelyi arqlatnrri 181 lcaspeyler hgkpesvsal vqhdclmiqe knsafgnwil tdgkqqthcr lngfhssnsg 241 svvliwalkg hgitlrsewd vaqyiergel vrvlpqwyqe aniwavytrr ssssdrikic 301 idfltehlaq clpggkapgv l