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MULTISPECIES: dipeptide/tripeptide permease DtpC


LOCUS       WP_000856824             485 aa            linear   BCT 29-FEB-2020
            [Enterobacteriaceae].
ACCESSION   WP_000856824
VERSION     WP_000856824.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 485)
  AUTHORS   Prabhala,B.K., Aduri,N.G., Jensen,J.M., Ernst,H.A., Iram,N.,
            Rahman,M. and Mirza,O.
  TITLE     New insights into the substrate specificities of proton-coupled
            oligopeptide transporters from E. coli by a pH sensitive assay
  JOURNAL   FEBS Lett. 588 (4), 560-565 (2014)
   PUBMED   24440353
REFERENCE   2  (residues 1 to 485)
  AUTHORS   Jensen,J.M., Simonsen,F.C., Mastali,A., Hald,H., Lillebro,I.,
            Diness,F., Olsen,L. and Mirza,O.
  TITLE     Biophysical characterization of the proton-coupled oligopeptide
            transporter YjdL
  JOURNAL   Peptides 38 (1), 89-93 (2012)
   PUBMED   22940668
REFERENCE   3  (residues 1 to 485)
  AUTHORS   Jensen,J.M., Ernst,H., Wang,X., Hald,H., Ditta,A.C., Ismat,F.,
            Rahman,M. and Mirza,O.
  TITLE     Functional investigation of conserved membrane-embedded glutamate
            residues in the proton-coupled peptide transporter YjdL
  JOURNAL   Protein Pept. Lett. 19 (3), 282-287 (2012)
   PUBMED   21933132
REFERENCE   4  (residues 1 to 485)
  AUTHORS   Ernst,H.A., Pham,A., Hald,H., Kastrup,J.S., Rahman,M. and Mirza,O.
  TITLE     Ligand binding analyses of the putative peptide transporter YjdL
            from E. coli display a significant selectivity towards dipeptides
  JOURNAL   Biochem. Biophys. Res. Commun. 389 (1), 112-116 (2009)
   PUBMED   19703419
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007789
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..485
                     /gene="dtpC"
     Protein         1..485
                     /product="dipeptide/tripeptide permease DtpC"
                     /calculated_mol_wt=52877
     Region          2..475
                     /region_name="MFS"
                     /note="Major Facilitator Superfamily; cl28910"
                     /db_xref="CDD:475125"
     Site            order(21,25,117,143,146..147,150,281,314..315,318,388)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340904"
ORIGIN      
        1 mktpsqprai yyivaiqiwe yfsfygmral lilylthqlg fddnhaislf sayaslvyvt
       61 pilggwladr llgnrtavia gallmtlghv vlgidtnstf slylalaiii cgyglfksni
      121 scllgelyde ndhrrdggfs llyaagnigs iaapiacgla aqwygwhvgf alagggmfig
      181 lliflsghrh fqstrsmdkk altsvkfalp vwswlvvmlc lapvfftlll endwsgylla
      241 ivcliaaqii armmikfpeh rralwqivll mfvgtlfwvl aqqggstisl fidrfvnrqa
      301 fnievptalf qsvnaiavml agvvlawlas peshgnstlr vwlkfafgll lmacgfmlla
      361 fdarhaaadg qasmgvmvsg lalmgfaelf idpvaiaqit rlkmsgvltg iymlatgava
      421 nwlagvvaqq ttesqisgma iaayqrffsq mgewtlacva iivvlafatr flfstptnmv
      481 qesnd