MULTISPECIES: type IV toxin-antitoxin system cytoskeleton-binding

LOCUS       WP_000854814             124 aa            linear   BCT 30-MAY-2022
            toxin CbtA [Gammaproteobacteria].
ACCESSION   WP_000854814
VERSION     WP_000854814.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 124)
  AUTHORS   Heller,D.M., Tavag,M. and Hochschild,A.
  TITLE     CbtA toxin of Escherichia coli inhibits cell division and cell
            elongation via direct and independent interactions with FtsZ and
            MreB
  JOURNAL   PLoS Genet 13 (9), e1007007 (2017)
   PUBMED   28931012
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 124)
  AUTHORS   Wen,Z., Wang,P., Sun,C., Guo,Y. and Wang,X.
  TITLE     Interaction of Type IV Toxin/Antitoxin Systems in Cryptic Prophages
            of Escherichia coli K-12
  JOURNAL   Toxins (Basel) 9 (3), E77 (2017)
   PUBMED   28257056
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 124)
  AUTHORS   Masuda,H., Tan,Q., Awano,N., Wu,K.P. and Inouye,M.
  TITLE     YeeU enhances the bundling of cytoskeletal polymers of MreB and
            FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli
  JOURNAL   Mol Microbiol 84 (5), 979-989 (2012)
   PUBMED   22515815
REFERENCE   4  (residues 1 to 124)
  AUTHORS   Tan,Q., Awano,N. and Inouye,M.
  TITLE     YeeV is an Escherichia coli toxin that inhibits cell division by
            targeting the cytoskeleton proteins, FtsZ and MreB
  JOURNAL   Mol Microbiol 79 (1), 109-118 (2011)
   PUBMED   21166897
REFERENCE   5  (residues 1 to 124)
  AUTHORS   Brown,J.M. and Shaw,K.J.
  TITLE     A novel family of Escherichia coli toxin-antitoxin gene pairs
  JOURNAL   J Bacteriol 185 (22), 6600-6608 (2003)
   PUBMED   14594833
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007774
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..124
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     gene            1..124
                     /gene="cbtA"
     Protein         1..124
                     /product="type IV toxin-antitoxin system
                     cytoskeleton-binding toxin CbtA"
                     /calculated_mol_wt=13768
     Region          1..108
                     /region_name="CbtA_toxin"
                     /note="CbtA_toxin of type IV toxin-antitoxin system;
                     pfam06755"
                     /db_xref="CDD:369065"
ORIGIN      
        1 mktlpvlpgq aassrpspve iwqillsrll dqhygltlnd tpfadervie qhieagislc
       61 davnflveky alvrtdqpgf sactrsqlin sidilrarra tglmtrdnyr tvnnitlgky
      121 peak