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MULTISPECIES: HyaD/HybD family hydrogenase maturation endopeptidase


LOCUS       WP_000852664             202 aa            linear   BCT 17-JUN-2024
            [Salmonella].
ACCESSION   WP_000852664
VERSION     WP_000852664.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 202)
  AUTHORS   Rousset,M., Dermoun,Z., Wall,J.D. and Belaich,J.P.
  TITLE     Analysis of the periplasmic [NiFe] hydrogenase transcription unit
            from Desulfovibrio fructosovorans
  JOURNAL   J Bacteriol 175 (11), 3388-3393 (1993)
   PUBMED   8501043
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00140.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..202
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..202
                     /gene="hybD"
     Protein         1..202
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /GO_component="GO:0009375 - ferredoxin hydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0051604 - protein maturation [Evidence
                     IEA]"
                     /calculated_mol_wt=22014
     Region          4..182
                     /region_name="H2MP"
                     /note="Hydrogenase specific C-terminal endopeptidases,
                     also called Hydrogen Maturation Proteases (H2MP). These
                     enzymes belong to the peptidase family M52. Maturation of
                     [FeNi] hydrogenases includes formation of the nickel
                     metallocenter, proteolytic processing...; cl00477"
                     /db_xref="CDD:444928"
     Site            order(11,25,41..43)
                     /site_type="active"
                     /note="putative substrate-binding site [active]"
                     /db_xref="CDD:99873"
     Site            order(17,63,94)
                     /site_type="other"
                     /note="nickel binding site [ion binding]"
                     /db_xref="CDD:99873"
ORIGIN      
        1 maevtilglg nllwadegfg vraaeklfeq yadnekvdvv dggtqglall pwlqqtekll
       61 imdaidfgma pgslamfrde qvpayltakk lslhqtsfse vlallqltgg qlseivligv
      121 qpeclddygg sltpqvkaql mpavylaqev laqwgitass aalpterlnh yslcmeryed
      181 erpdaqsacr vgdirvlqre ks