MULTISPECIES: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione

LOCUS       WP_000849477             646 aa            linear   BCT 01-JUL-2024
            acylhydrolase (decyclizing) [Salmonella].
ACCESSION   WP_000849477
VERSION     WP_000849477.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 646)
  AUTHORS   Yoshida,K., Yamaguchi,M., Morinaga,T., Kinehara,M., Ikeuchi,M.,
            Ashida,H. and Fujita,Y.
  TITLE     myo-Inositol catabolism in Bacillus subtilis
  JOURNAL   J Biol Chem 283 (16), 10415-10424 (2008)
   PUBMED   18310071
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR04377.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..646
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..646
                     /gene="iolD"
     Protein         1..646
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /EC_number="3.7.1.22"
                     /GO_function="GO:0016823 - hydrolase activity, acting on
                     acid carbon-carbon bonds, in ketonic substances [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=72231
     Region          1..646
                     /region_name="IolD"
                     /note="TPP-dependent trihydroxycyclohexane-1,2-dione
                     (THcHDO) dehydratase, myo-inositol metabolism
                     [Carbohydrate transport and metabolism]; COG3962"
                     /db_xref="CDD:443162"
ORIGIN      
        1 mktirltmaq alvrfldnqy idvdgseikf vkgifaifgh gnvvglgqal eedcgqlsvh
       61 qgrneqgmah iatgfarqmr rhqiyactss vgpgaanmit aaatatanri pllllpgdvy
      121 asrqpdpvlq qveqehdltl stndafravs rywdritrpe qlmsacisam rvltdpadtg
      181 avtlclpqdv qgeawdypdy ffarrvyrle rhaptepmln eavalirrhq rplivcgggv
      241 kysqaeeall rfaerchlpi aetqagkgal ssahplnvgg igetgslaan llaqeadlii
      301 gvgtrytdft tsskwifqnp dvrylninvs rfdvfkldgv qmqgdarval tqlserlaqe
      361 hyasqwgeti hrvrsqymae vervyaveys gegfkpeied hmdtqkvfee fneitrswlt
      421 qtrvlgvlnr mlpenalvva aagslpgdlq rvwqsrgend yhveygyscm gyevnaalga
      481 klaqperevy sfvgdgsfmm lhselvtsvq mgkkitvill dnmtngcinn lqmehgmdsy
      541 ftefrfhqqe sgrqeggfip vdfariaegy gcksyrvtti eqlhealeda rkqtvstlid
      601 ikvlpktmvh kylswwrvgg aqvsrseriq avarmleehi gqarqy