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MULTISPECIES: 2-iminoacetate synthase ThiH [Shigella].


LOCUS       WP_000847552             377 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_000847552
VERSION     WP_000847552.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 377)
  AUTHORS   Leonardi,R. and Roach,P.L.
  TITLE     Thiamine biosynthesis in Escherichia coli: in vitro reconstitution
            of the thiazole synthase activity
  JOURNAL   J Biol Chem 279 (17), 17054-17062 (2004)
   PUBMED   14757766
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02351.2
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..377
                     /gene="thiH"
     Protein         1..377
                     /product="2-iminoacetate synthase ThiH"
                     /GO_function="GO:0005506 - iron ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=43234
     Region          3..369
                     /region_name="thiH"
                     /note="thiazole biosynthesis protein ThiH; TIGR02351"
                     /db_xref="CDD:131404"
ORIGIN      
        1 mktfsnrwrq ldwddirlri ngktaadver alnasqltrd dmmallspaa sgyleqlaqq
       61 aqrltrqrfg ntvsfyvply lsnlcandct ycgfsmsnri krktldeadi aresaairem
      121 gfehlllvtg ehqakvgmdy frrhlpalre qfsslqmevq plaeteyael kqlgldgvmv
      181 yqetyheaty trhhlkgkkq dffwrletpd rlgragidki glgaliglsd nwrvdcymva
      241 ehllwlqqhy wqsrysvsfp rlrpctggie pasimderql vqticafrll apeielslst
      301 respwfrdrv iplainnvsa fsktqpggya dnhpeleqfs phddrrpeav aavltaqglq
      361 pvwkdwdsyl grasqrl