2-iminoacetate synthase ThiH [Escherichia coli].

LOCUS       WP_000847449             377 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_000847449
VERSION     WP_000847449.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 377)
  AUTHORS   Leonardi,R. and Roach,P.L.
  TITLE     Thiamine biosynthesis in Escherichia coli: in vitro reconstitution
            of the thiazole synthase activity
  JOURNAL   J Biol Chem 279 (17), 17054-17062 (2004)
   PUBMED   14757766
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02351.2
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..377
                     /gene="thiH"
     Protein         1..377
                     /product="2-iminoacetate synthase ThiH"
                     /GO_function="GO:0005506 - iron ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=43192
     Region          3..369
                     /region_name="thiH"
                     /note="thiazole biosynthesis protein ThiH; TIGR02351"
                     /db_xref="CDD:131404"
ORIGIN      
        1 mktfsdrwrq ldwddirlri ngktaadver alnasqltrd dmmallspaa sgyleqlaqr
       61 aqrltrqrfg ntvsfyvply lsnlcandct ycgfsmsnri krktldeadi aresaairem
      121 gfehlllvtg ehqakvgmdy frrhlpalre qfsslqmevq plaeteyael kqlgldgvmv
      181 yqetyheaty arhhlkgkkq dffwrletpd rlgragidki glgaliglsd swrvdcymva
      241 ehllwlqqhy wqsrysvsfp rlrpctggie pasimderql vqticafrll apeielslst
      301 respwfrdrv iplainnvsa fsktqpggya dnhpeleqfs phderrpeav aaaltaqglq
      361 pvwkdwdsyl grasqrl