MULTISPECIES: S-(hydroxymethyl)glutathione dehydrogenase

LOCUS       WP_000842106             369 aa            linear   BCT 20-NOV-2023
            [Escherichia].
ACCESSION   WP_000842106
VERSION     WP_000842106.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 369)
  AUTHORS   Herring,C.D. and Blattner,F.R.
  TITLE     Global transcriptional effects of a suppressor tRNA and the
            inactivation of the regulator frmR
  JOURNAL   J. Bacteriol. 186 (20), 6714-6720 (2004)
   PUBMED   15466022
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to P25437.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011002
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..369
                     /gene="frmA"
     Protein         1..369
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /EC_number="1.1.1.284"
                     /calculated_mol_wt=39228
     Region          1..368
                     /region_name="alcohol_DH_class_III"
                     /note="class III alcohol dehydrogenases; cd08300"
                     /db_xref="CDD:176260"
     Site            order(40,42,51..53,62,88..89,169,289,313)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:176260"
     Site            order(40,62..63,169)
                     /site_type="other"
                     /note="catalytic Zn binding site [ion binding]"
                     /db_xref="CDD:176260"
     Site            order(41..42,169,173,194..198,218..219,223,263..264,
                     268..269,287..288,312..314,364)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:176260"
     Site            order(92,95,98,106)
                     /site_type="other"
                     /note="structural Zn binding site [ion binding]"
                     /db_xref="CDD:176260"
     Site            order(96..97,100,102..103,105,107,254,259,270..271,
                     278..281,290,293..300,303..305,308..313)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:176260"
ORIGIN      
        1 mksraavafa pgkpleivei dvappkkgev likvthtgvc htdaftlsgd dpegvfpvvl
       61 ghegagvvve vgegvtsvkp gdhviplyta ecgecefcrs gktnlcvavr etqgkglmpd
      121 gttrfsyngq plyhymgcst fseytvvaev slakinpean hehvcllgcg vttgigavhn
      181 takvqpgdsv avfglgaigl avvqgarqak agriiaidtn pkkfdlarrf gatdcinpnd
      241 ydkpikdvll dinkwgidht fecignvnvm raalesahrg wgqsviigva vagqeistrp
      301 fqlvtgrvwk gsafggvkgr sqlpgmveda mkgdidlepf vthtmsldei ndafdlmheg
      361 ksirtviry