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ABC transporter substrate-binding protein [Escherichia coli].


LOCUS       WP_000830577             516 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_000830577
VERSION     WP_000830577.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 516)
  AUTHORS   Maqbool,A., Horler,R.S., Muller,A., Wilkinson,A.J., Wilson,K.S. and
            Thomas,G.H.
  TITLE     The substrate-binding protein in bacterial ABC transporters:
            dissecting roles in the evolution of substrate specificity
  JOURNAL   Biochem Soc Trans 43 (5), 1011-1017 (2015)
   PUBMED   26517916
REFERENCE   2  (residues 1 to 516)
  AUTHORS   Wilkens,S.
  TITLE     Structure and mechanism of ABC transporters
  JOURNAL   F1000Prime Rep 7, 14 (2015)
   PUBMED   25750732
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 516)
  AUTHORS   ter Beek,J., Guskov,A. and Slotboom,D.J.
  TITLE     Structural diversity of ABC transporters
  JOURNAL   J Gen Physiol 143 (4), 419-435 (2014)
   PUBMED   24638992
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10170729
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..516
                     /product="ABC transporter substrate-binding protein"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /calculated_mol_wt=57497
     Region          28..499
                     /region_name="PBP2_NikA_DppA_OppA_like_7"
                     /note="The substrate-binding component of an
                     uncharacterized ABC-type
                     nickel/dipeptide/oligopeptide-like import system contains
                     the type 2 periplasmic binding fold; cd08512"
                     /db_xref="CDD:173877"
ORIGIN      
        1 mkrsisfrpt llalvlattf pvahaavpkd mlvigkaadp qtldpavtid nndwtvtyps
       61 yqrlvqyktd gdkgstdveg dlasswkasn dqkewtftlk dnakfadgtp vtaeavklsf
      121 erllkigqgp aeafpkdlki dapdehtvkf tlsqpfapfl ytlandgasi inpavlkeha
      181 addargflaq ntagsgpfml kswqkgqqlv lvpnphypgn kpnfkrvsvk iigesasrrl
      241 qlsrgdidia dalpvdqlna lkqenkvnva eypslrvtyl ylnnskapln qadlrraisw
      301 stdyqgmvng ilsgngkqmr gpipegmwgy datamqynhd etkakaewdk vtskptsltf
      361 lysdndpnwe pialatqssl nklginvkle klanatmrdr vgkgdydiai gnwspdfadp
      421 ymfmnywfes dkkglpgnrs fyensevdkl lrnalattdq tqrtrdyqqa qkividdaay
      481 vylfqknyql amnkevkgfv fnpmleqvfn intmsk