MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_000824240             428 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000824240
VERSION     WP_000824240.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 428)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 428)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 428)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022908
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..428
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=46330
     Region          8..411
                     /region_name="MFS_ExuT_GudP_like"
                     /note="Hexuronate transporter, Glucarate transporter, and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17319"
                     /db_xref="CDD:340877"
     Site            order(21..22,25..26,29,61,111..112,114..116,119,139,
                     142..143,146,236,239..240,243..245,248,276,280,338..339,
                     343,347,363,366..367,370..371,374)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340877"
ORIGIN      
        1 mkrktmgwli vfllfivyml nymdrsalsi tapliekelg fnaaemgmif saffigyalf
       61 nfiggwasdk vgpktvflia allwsvfcgl tglvtglwtm livrvlfgma egpvsaagnk
      121 iinnwisrke sataigifsa gsplggavsg pivgllalsl gwrpafgiif lfglvwvllw
      181 yfivsdkptm skrlapeeri dfenhedvil sddgratpsl gyymkqpmvw attlaffsyn
      241 yilfffltwf psylnhslhl dikeisiatv ipwvigaigm vlggvcsdvi yritgnalls
      301 rrlilgvcla gaavcvavsg tvstigsait lmsvslflly ltgpiywavi qdvvhkdkvg
      361 svggamhgla nisgiigplv tgfivqfsgk ydyafylaga iaivssllvf vfvkskgfka
      421 nesqscvh