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DNA-binding transcriptional regulator PgrR [Escherichia coli].


LOCUS       WP_000817685             299 aa            linear   BCT 24-FEB-2020
ACCESSION   WP_000817685
VERSION     WP_000817685.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 299)
  AUTHORS   Shimada,T., Yamazaki,K. and Ishihama,A.
  TITLE     Novel regulator PgrR for switch control of peptidoglycan recycling
            in Escherichia coli
  JOURNAL   Genes Cells 18 (2), 123-134 (2013)
   PUBMED   23301696
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011266
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..299
                     /gene="pgrR"
     Protein         1..299
                     /product="DNA-binding transcriptional regulator PgrR"
                     /calculated_mol_wt=33345
     Region          6..65
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          92..293
                     /region_name="PBP2_CrgA_like_5"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08474"
                     /db_xref="CDD:176163"
     Site            order(104,108,147,161,164,228,245,272)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176163"
     Site            order(105..106,110..111,113..114,117,121,123..129,191,
                     222..226,233..234,237)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176163"
ORIGIN      
        1 mkreeiadlm afvvvaeers ftraaarlsm aqsalsqivr rieerlglrl ltrttrsvvp
       61 teagehllsv lgpmlhdids alaslsdlqn rpsgtiritt vehaaktill pamrtflksh
      121 peidiqliid ygltdvvser fdagvrlgge mdkdmiairi gpdipmaivg spdyfsrrsv
      181 ptsvsqlidh qainlylpts gtanrwrlir ggrevrvrme gqlllntidl iidaaidghg
      241 laylpydqve raikekklir vldkftpdlp gyhlyyphrr hagsafslfi drlkykgav