Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

5-(carboxyamino)imidazole ribonucleotide synthase [Escherichia


LOCUS       WP_000815575             355 aa            linear   BCT 02-JUN-2019
            coli].
ACCESSION   WP_000815575
VERSION     WP_000815575.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF004678.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK06019
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..355
                     /gene="purK"
     Protein         1..355
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /EC_number="6.3.4.18"
                     /GO_function="GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=39441
     Region          1..335
                     /region_name="PRK06019"
                     /note="phosphoribosylaminoimidazole carboxylase ATPase
                     subunit; Reviewed"
                     /db_xref="CDD:235674"
ORIGIN      
        1 mkqvcvlgng qlgrmlrqag eplgiavwpv gldaepaavp fqqsvitaei erwpetaltr
       61 elarhpafvn rdvfpiiadr ltqkqlfdkl hlptapwqll aersewpavf erlgelaivk
      121 rrtggydgrg qwrlradete qlpaecygec iveqginfsg evslvgarcf dgstvfyplt
      181 hnlhqdgilr tsvafpqana qqqaqaeeml saimqelgyv gvmamecfvt pqgllinela
      241 prvhnsghwt qngasisqfe lhlraitdlp lpqpvvnnps vminligsdv nydwlklplv
      301 hlhwydkevr pgrkvghlnl tdsdtsrlsa tlealipllp peyasgvmwa qskfc