MULTISPECIES: 1-deoxy-D-xylulose-5-phosphate reductoisomerase

LOCUS       WP_000811905             398 aa            linear   BCT 28-MAR-2022
            [Salmonella].
ACCESSION   WP_000811905
VERSION     WP_000811905.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 398)
  AUTHORS   Haymond,A., Johny,C., Dowdy,T., Schweibenz,B., Villarroel,K.,
            Young,R., Mantooth,C.J., Patel,T., Bases,J., San Jose,G.,
            Jackson,E.R., Dowd,C.S. and Couch,R.D.
  TITLE     Kinetic characterization and allosteric inhibition of the Yersinia
            pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP
            synthase)
  JOURNAL   PLoS One 9 (8), e106243 (2014)
   PUBMED   25171339
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003938.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05447
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..398
                     /gene="ispC"
     Protein         1..398
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /EC_number="1.1.1.267"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070402 - NADPH binding [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=43222
     Region          1..398
                     /region_name="PRK05447"
                     /note="1-deoxy-D-xylulose 5-phosphate reductoisomerase;
                     Provisional"
                     /db_xref="CDD:235472"
ORIGIN      
        1 mkqltilgst gsigcstldv vrhnpdsfrv ialvagknva rmaeqclefs pryavmddts
       61 saeqlkimlq qhgsrtevls gqqaacemaa ldevghvmaa ivgaagllpt laairagkti
      121 llankeslvt cgrlfmdevk rsnarllpvd sehnaifqsl pqsiqhnlgy adleqngvts
      181 illtgsggpf retpmcdlaa mtpdqacrhp nwsmgrkisv dsatmmnkgl eyiearwlfn
      241 asarqmevli hpqsvihsmv ryqdgsvlaq lgepdmrtpi ahtmawpnrv tsgaqpldfc
      301 klsaltfsap dyqrypclkl ameafeqgqa attalnaane itvaaflaqq irftdiagln
      361 lavlermdlq epasvedvlq vdaiarevar kqvirlsr